Literature DB >> 6126807

Effect of calmodulin inhibitor, Stelazine, on the endocytosis of vitellogenin and transglutaminase activity in Xenopus laevis oöcytes.

L M Tucciarone, K D Lanclos.   

Abstract

The specific endocytosis of vitellogenin was measured in the presence of various concentrations of Stelazine, a specific inhibitor of the calcium regulating protein, calmodulin. Stelazine (200 microM) was found to inhibit the endocytosis of vitellogenin by 63% as determined by decreased uptake of vitellogenin into transitional yolk bodies and yolk platelets. The enzymatic activity of transglutaminase, a calcium-requiring enzyme implicated in receptor-mediated endocytosis, was not affected by these concentrations of Stelazine.

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Year:  1982        PMID： 6126807     DOI： 10.1007/bf00230084

Source DB:  PubMed          Journal:  Mol Cell Biochem        ISSN： 0300-8177            Impact factor:   3.396


  10 in total

1.  Protein incorporation by isolated amphibian oocytes. 3. Optimum incubation conditions.

Authors:  R A Wallace; D W Jared; J N Dumont; M W Sega
Journal:  J Exp Zool       Date:  1973-06

2.  Protein incorporation by isolated amphibian oocytes. I. Preliminary studies.

Authors:  R A Wallace; D W Jared; B L Nelson
Journal:  J Exp Zool       Date:  1970-11

3.  Transglutaminase is essential in receptor-mediated endocytosis of alpha 2-macroglobulin and polypeptide hormones.

Authors:  P J Davies; D R Davies; A Levitzki; F R Maxfield; P Milhaud; M C Willingham; I H Pastan
Journal:  Nature       Date:  1980-01-10       Impact factor: 49.962

4.  Evidence for the involvement of transglutaminase in the uptake of vitellogenin by Xenopus laevis oocytes.

Authors:  L M Tucciarone; K D Lanclos
Journal:  Biochem Biophys Res Commun       Date:  1981-03-16       Impact factor: 3.575

5.  Long-term growth and differentiation of Xenopus oocytes in a defined medium.

Authors:  R A Wallace; Z Misulovin
Journal:  Proc Natl Acad Sci U S A       Date:  1978-11       Impact factor: 11.205

6.  Interactions of calmodulin with coated vesicles from brain.

Authors:  C D Linden; J R Dedman; J G Chafouleas; A R Means; T F Roth
Journal:  Proc Natl Acad Sci U S A       Date:  1981-01       Impact factor: 11.205

7.  Differential postendocytotic compartmentation in Xenopus oocytes is mediated by a specifically bound ligand.

Authors:  L Opresko; H S Wiley; R A Wallace
Journal:  Cell       Date:  1980-11       Impact factor: 41.582

8.  Protein and cell membrane iodinations with a sparingly soluble chloroamide, 1,3,4,6-tetrachloro-3a,6a-diphrenylglycoluril.

Authors:  P J Fraker; J C Speck
Journal:  Biochem Biophys Res Commun       Date:  1978-02-28       Impact factor: 3.575

9.  Protein incorporation by isolated amphibian oocytes. V. Specificity for vitellogenin incorporation.

Authors:  R A Wallace; D W Jared
Journal:  J Cell Biol       Date:  1976-05       Impact factor: 10.539

10.  Role of coated vesicles, microfilaments, and calmodulin in receptor-mediated endocytosis by cultured B lymphoblastoid cells.

Authors:  J L Salisbury; J S Condeelis; P Satir
Journal:  J Cell Biol       Date:  1980-10       Impact factor: 10.539
  10 in total
  1 in total

1.  Are pharmaceuticals with evolutionary conserved molecular drug targets more potent to cause toxic effects in non-target organisms?

Authors:  Sara Furuhagen; Anne Fuchs; Elin Lundström Belleza; Magnus Breitholtz; Elena Gorokhova
Journal:  PLoS One       Date:  2014-08-20       Impact factor: 3.240
  1 in total

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