The number and distribution of Brugia pahangi in cats at different times after a primary infection.

The number of larvae and adults of Brugia pahangi and their distribution throughout the lymphatics and extra-lymphatic tissue were studied in cats infected by subcutaneous injection of larvae into their hind feet. For the first 20 days approximately 55% of the inoculum is recovered as living worms. After 25 days the recovery falls by a half. It is suggested that this loss of worms may be due to either the developing immunological response or the moult from the 4th to the 5th stage. Larvae penetrate the lymphatics rapidly (50% within 3 h) and migrate to the popliteal lymph node after about 20 days they migrate back down into the afferent lymphatic.