Literature DB >> 6125559

Some properties of glutathione biosynthesis-deficient mutants of Escherichia coli B.

K Murata, A Kimura.   

Abstract

Mutants of Escherichia coli B that contain essentially no detectable glutathione were isolated. These mutants had a very low activity of gamma-glutamylcysteine synthetase or glutathione synthetase. No significant differences in growth in minimal medium were observed between the mutants and the parental strain. The mutants lacking gamma-glutamylcysteine synthetase activity were more susceptible to toxic compounds than either the parental strain or a glutathione synthetase-deficient strain. The mutants lacking gamma-glutamylcysteine synthetase activity were also susceptible to oxygen.

Entities:  

Mesh：

Substances：

Year:  1982        PMID： 6125559     DOI： 10.1099/00221287-128-5-1047

Source DB:  PubMed          Journal:  J Gen Microbiol        ISSN： 0022-1287


  9 in total

1.  Efficient production of glutathione with multi-pathway engineering in Corynebacterium glutamicum.

Authors:  Wei Liu; Xiangcheng Zhu; Jiazhang Lian; Lei Huang; Zhinan Xu
Journal:  J Ind Microbiol Biotechnol       Date:  2019-08-16       Impact factor: 3.346

2.  The evolution of glutathione metabolism in phototrophic microorganisms.

Authors:  R C Fahey; R M Buschbacher; G L Newton
Journal:  J Mol Evol       Date:  1987       Impact factor: 2.395

3.  Glutathione is required for maximal transcription of the cobalamin biosynthetic and 1,2-propanediol utilization (cob/pdu) regulon and for the catabolism of ethanolamine, 1,2-propanediol, and propionate in Salmonella typhimurium LT2.

Authors:  M R Rondon; R Kazmierczak; J C Escalante-Semerena
Journal:  J Bacteriol       Date:  1995-10       Impact factor: 3.490

4.  Glutathione status and sensitivity to GSH-reacting compounds of Escherichia coli strains deficient in glutathione metabolism and/or catalase activity.

Authors:  A Alonso-Moraga; A Bocanegra; J M Torres; J López-Barea; C Pueyo
Journal:  Mol Cell Biochem       Date:  1987-01       Impact factor: 3.396

5.  Functional analysis of the gamma-glutamylcysteine synthetase of Escherichia coli B: effect of substitution of His-150 to Ala.

Authors:  Y Inoue; Y Iba; H Yano; K Murata; A Kimura
Journal:  Appl Microbiol Biotechnol       Date:  1993-01       Impact factor: 4.813

6.  Cloning of a gene responsible for the biosynthesis of glutathione in Escherichia coli B.

Authors:  K Murata; A Kimura
Journal:  Appl Environ Microbiol       Date:  1982-12       Impact factor: 4.792

7.  The nucleotide sequence of the gene for gamma-glutamylcysteine synthetase of Escherichia coli.

Authors:  K Watanabe; Y Yamano; K Murata; A Kimura
Journal:  Nucleic Acids Res       Date:  1986-06-11       Impact factor: 16.971

Review 8.  Oxygen regulated gene expression in facultatively anaerobic bacteria.

Authors:  G Unden; S Becker; J Bongaerts; J Schirawski; S Six
Journal:  Antonie Van Leeuwenhoek       Date:  1994       Impact factor: 2.271

9.  Systematic manipulation of glutathione metabolism in Escherichia coli for improved glutathione production.

Authors:  Jing Zhang; Cong Quan; Cheng Wang; Hui Wu; Zhimin Li; Qin Ye
Journal:  Microb Cell Fact       Date:  2016-02-16       Impact factor: 5.328
  9 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.