Literature DB >> 6125393

Effects of the H2 receptor antagonist ranitidine on anterior pituitary hormone secretion in man.

G Delitala, L Devilla, A Pende, A Canessa.   

Abstract

The effect of an i.v. bolus of the H2-receptor antagonist ranitidine 50, 100, 200 and 300 mg on serum levels of prolactin, TSH, GH, LH, FSH and cortisol was studied in 12 normal males. Ranitidine 200 and 300 mg significantly stimulated prolactin release without affecting any of the other hormones. Ranitidine 300 mg caused a rise in prolactin comparable to that observed following cimetidine 200 mg. The results show that ranitidine releases prolactin in man, but only when a large intravenous injection is given.

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Year:  1982        PMID: 6125393     DOI: 10.1007/bf00545216

Source DB:  PubMed          Journal:  Eur J Clin Pharmacol        ISSN: 0031-6970            Impact factor:   2.953


  14 in total

1.  Effects of acute and chronic cimetidine administration on the pituitary-testicular axis.

Authors:  J C Daubresse; J C Meunier; G Ligny
Journal:  Agressologie       Date:  1979

2.  Prolactin and luteinizing hormone release after intraventricular injection of histamine in rats.

Authors:  A O Donoso; A M Banzan; M I Borzino
Journal:  J Endocrinol       Date:  1976-01       Impact factor: 4.286

3.  The pharmacology of cimetidine, a new histamine H2-receptor antagonist.

Authors:  R W Brimblecombe; W A Duncan; G J Durant; C R Ganellin; M E Parsons; J W Black
Journal:  Br J Pharmacol       Date:  1975-03       Impact factor: 8.739

4.  The effects of ranitidine on pituitary hormone secretion in vitro.

Authors:  T Yeo; G Delitala; G M Besser; C R Edwards
Journal:  Br J Clin Pharmacol       Date:  1980-08       Impact factor: 4.335

5.  Gastric inhibitory action of H2-antagonists ranitidine and cimetidine.

Authors:  W Domschke; G Lux; S Domschke
Journal:  Lancet       Date:  1979-02-10       Impact factor: 79.321

6.  Failure of cimetidine to antagonise dopamine-induced suppression of prolactin in vitro.

Authors:  G Delitala; W A Stubbs; T Yeo; A Jones; G M Besser
Journal:  Br J Clin Pharmacol       Date:  1979-01       Impact factor: 4.335

7.  Cimetidine, an H2-antihistamine, stimulates prolactin secretion in man.

Authors:  H E Carlson; A F Ippoliti
Journal:  J Clin Endocrinol Metab       Date:  1977-08       Impact factor: 5.958

8.  Effects of the H2 receptor antagonist cimetidine on pituitary hormones in man.

Authors:  G Delitala; W A Stubbs; J A Wass; A Jones; S Williams; G M Besser
Journal:  Clin Endocrinol (Oxf)       Date:  1979       Impact factor: 3.478

9.  H1 and H2 histamine receptor participation in the brain control of prolactin secretion in lactating rats.

Authors:  M C Arakelian; C Libertun
Journal:  Endocrinology       Date:  1977-03       Impact factor: 4.736

10.  H1- and H2-histamine receptor antagonists and induced release of prolactin in male rats.

Authors:  A O Donoso; A M Banzan
Journal:  Neuroendocrinology       Date:  1980       Impact factor: 4.914

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  8 in total

1.  Plasma prolactin, sex steroids and gastrin in human volunteers treated for 2 weeks with therapeutic doses of cimetidine or the new histamine H2-receptor antagonist ramixotidine (CM 57755A).

Authors:  M Colle; E Ruedas; J Cazenave; J Auzerie; G Basilisco; G Camboni; L Manara
Journal:  Eur J Clin Pharmacol       Date:  1988       Impact factor: 2.953

Review 2.  Famotidine. An updated review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use in peptic ulcer disease and other allied diseases.

Authors:  H D Langtry; S M Grant; K L Goa
Journal:  Drugs       Date:  1989-10       Impact factor: 9.546

3.  Cimetidine and ranitidine on basal and ACTH-stimulated steroidogenesis.

Authors:  R G Karlstadt; W O Frank; L A Antell; S W Shapowal; R H Palmer
Journal:  Gut       Date:  1987-12       Impact factor: 23.059

Review 4.  Side effects of ranitidine.

Authors:  T Vial; C Goubier; A Bergeret; F Cabrera; J C Evreux; J Descotes
Journal:  Drug Saf       Date:  1991 Mar-Apr       Impact factor: 5.606

Review 5.  Ranitidine. An updated review of its pharmacodynamic and pharmacokinetic properties and therapeutic use in peptic ulcer disease and other allied diseases.

Authors:  S M Grant; H D Langtry; R N Brogden
Journal:  Drugs       Date:  1989-06       Impact factor: 9.546

6.  The role of ranitidine infusion on glucose, insulin and C-peptide serum levels induced by oral glucose tolerance test in healthy subjects.

Authors:  S Gentile; R Marmo; A Costume; C Orlando; R D'Alessandro; G De Bellis; M Porcellini; M Coltorti
Journal:  Acta Diabetol Lat       Date:  1986 Apr-Jun

7.  Ranitidine treatment and cortisol metabolism in man.

Authors:  H Mönig; K Hoffmann; E E Ohnhaus; H M Schulte
Journal:  Eur J Drug Metab Pharmacokinet       Date:  1992 Jan-Mar       Impact factor: 2.441

Review 8.  Adverse reactions and interactions with H2-receptor antagonists.

Authors:  J Penston; K G Wormsley
Journal:  Med Toxicol       Date:  1986 May-Jun
  8 in total

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