Literature DB >> 6123839

Cytomegalovirus and Kaposi's sarcoma in young homosexual men.

W L Drew, M A Conant, R C Miner, E S Huang, J L Ziegler, J R Groundwater, J H Gullett, P Volberding, D I Abrams, L Mintz.   

Abstract

10 homosexual men with Kaposi's sarcoma (KS) were studied for evidence of cytomegalovirus (CMV) infection. IgG and IgM antibodies to CMV were detected in 9 out of 9 and in 7 out of 9 of these patients, respectively. CMV was recovered from body secretions or peripheral blood of 7 patients. Viral cultures of KS tumour biopsy specimens were negative in 8 out of 8 patients, but CMV RNA was detected by in-situ hybridisation in 2 out of 3 and CMV antigen(s) by immunofluorescence in 6 out of 9. Normal tissue specimens from 3 KS patients were negative for CMV antigen. These observations suggest an association of CMV with KS.

Entities:  

Mesh：

Substances：

Year:  1982        PMID： 6123839     DOI： 10.1016/s0140-6736(82)91092-3

Source DB:  PubMed          Journal:  Lancet        ISSN： 0140-6736            Impact factor:   79.321


  34 in total

1.  In situ hybridization analysis of cytomegalovirus lytic infection in Kaposi's sarcoma associated with AIDS. A study of 14 autopsy cases.

Authors:  H Hashimoto; H Müller; F Müller; H L Schmidts; H J Stutte
Journal:  Virchows Arch A Pathol Anat Histopathol       Date:  1987

2.  Confirmation of human cytomegalovirus by reverse passive hemagglutination with monoclonal antibodies reactive to the major glycosylated peptide (GP-66).

Authors:  K S Kim; V Sapienza; C M Chen
Journal:  J Clin Microbiol       Date:  1986-09       Impact factor: 5.948

3.  Detection of herpesvirus-like DNA in HIV-associated and classical Kaposi's sarcoma.

Authors:  M Simon; P Kind; P Kaudewitz; A Graf; C G Schirren; M Raffeld; C A Sander
Journal:  Arch Dermatol Res       Date:  1996-06       Impact factor: 3.017

4.  Implausibility of an aetiological association between cytomegalovirus and Kaposi's sarcoma shown by four techniques.

Authors:  F Van den Berg; M Schipper; M Jiwa; R Rook; F Van de Rijke; B Tigges
Journal:  J Clin Pathol       Date:  1989-02       Impact factor: 3.411

5.  Activation of Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) lytic replication by human cytomegalovirus.

Authors:  J Vieira; P O'Hearn; L Kimball; B Chandran; L Corey
Journal:  J Virol       Date:  2001-02       Impact factor: 5.103

6.  Detection of DNA of lymphotropic herpesviruses in plasma of human immunodeficiency virus-infected patients: frequency and clinical significance.

Authors:  Francesco Broccolo; Simona Bossolasco; Anna M Careddu; Giuseppe Tambussi; Adriano Lazzarin; Paola Cinque
Journal:  Clin Diagn Lab Immunol       Date:  2002-11

7.  Kaposi's sarcoma and malignant lymphoma in AIDS.

Authors:  H J Leu; J Schneider; T Hardmeier; R Maurer; R Lüthy; R Burger; H R Burger; M Krause
Journal:  Virchows Arch A Pathol Anat Histopathol       Date:  1984

8.  Cytomegalovirus infection induces high levels of cyclins, phosphorylated Rb, and p53, leading to cell cycle arrest.

Authors:  F M Jault; J M Jault; F Ruchti; E A Fortunato; C Clark; J Corbeil; D D Richman; D H Spector
Journal:  J Virol       Date:  1995-11       Impact factor: 5.103

9.  Evaluation of abdominal pain in the AIDS patient.

Authors:  D A Potter; D N Danforth; A M Macher; D L Longo; L Stewart; H Masur
Journal:  Ann Surg       Date:  1984-03       Impact factor: 12.969

Review 10.  Human herpesvirus-8: detection of novel herpesvirus-like DNA sequences in Kaposi's sarcoma and other lesions.

Authors:  O M Memar; P L Rady; S K Tyring
Journal:  J Mol Med (Berl)       Date:  1995-12       Impact factor: 4.599
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.