Literature DB >> 6123152

Biotin enhances guanylate cyclase activity.

D L Vesely.   

Abstract

Biotin and its analog, (+)-biotin-p-nitrophenyl ester enhanced guanylate cyclase activity two- to threefold in rat liver, kidney, colon, cerebellum, and heart. Dose-response relationships revealed that at concentrations as low as 1 micromolar, both biotin and its analog caused maximal augmentation of guanylate cyclase activity. These data suggest a role for the activation of guanylate cyclase in the mechanism of action of this vitamin.

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Year:  1982        PMID： 6123152     DOI： 10.1126/science.6123152

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  17 in total

1.  Construction of a Biotin-Overproducing Strain of Serratia marcescens.

Authors:  N Sakurai; Y Imai; M Masuda; S Komatsubara; T Tosa
Journal:  Appl Environ Microbiol       Date:  1993-09       Impact factor: 4.792

2.  Effect of biotin on glucokinase activity, mRNA expression and insulin release in cultured beta-cells.

Authors:  P Borboni; R Magnaterra; R A Rabini; R Staffolani; O Porzio; G Sesti; A Fusco; L Mazzanti; R Lauro; L N Marlier
Journal:  Acta Diabetol       Date:  1996-07       Impact factor: 4.280

3.  Production and characterization of a monoclonal antibody to biotin.

Authors:  K Dakshinamurti; R P Bhullar; A Scoot; E S Rector; G Delespesse; A H Sehon
Journal:  Biochem J       Date:  1986-07-15       Impact factor: 3.857

4.  Stimulation of guanylate cyclase and RNA polymerase II activities in HeLa cells and fibroblasts by biotin.

Authors:  I N Singh; K Dakshinamurti
Journal:  Mol Cell Biochem       Date:  1988-01       Impact factor: 3.396

Review 5.  Intestinal absorption of water-soluble vitamins in health and disease.

Authors:  Hamid M Said
Journal:  Biochem J       Date:  2011-08-01       Impact factor: 3.857

6.  Nitric oxide signaling depends on biotin in Jurkat human lymphoma cells.

Authors:  Rocio Rodriguez-Melendez; Janos Zempleni
Journal:  J Nutr       Date:  2009-01-13       Impact factor: 4.798

7.  Biotin analogs activate guanylate cyclase.

Authors:  D L Vesely; H C Wormser; H N Abramson
Journal:  Mol Cell Biochem       Date:  1984       Impact factor: 3.396

8.  Targeting aspirin resistance with nutraceuticals: a possible strategy for reducing cardiovascular morbidity and mortality.

Authors:  James J DiNicolantonio; James H O'Keefe; Mark F McCarty
Journal:  Open Heart       Date:  2017-09-02

9.  Supplementation with Phycocyanobilin, Citrulline, Taurine, and Supranutritional Doses of Folic Acid and Biotin-Potential for Preventing or Slowing the Progression of Diabetic Complications.

Authors:  Mark F McCarty
Journal:  Healthcare (Basel)       Date:  2017-03-14

10.  Autophagy-induced degradation of Notch1, achieved through intermittent fasting, may promote beta cell neogenesis: implications for reversal of type 2 diabetes.

Authors:  James J DiNicolantonio; Mark McCarty
Journal:  Open Heart       Date:  2019-05-22
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