Literature DB >> 6123137

Effect of somatostatin on the secretin-induced gastric secretions of pepsin and mucus in cats.

M Vagne, C Roche, J A Chayvialle, C Gespach.   

Abstract

The effect of somatostatin 14 on gastric stimulation produced by secretin was determined in 6 conscious cats equipped with a gastric fistula and a denervated fundic pouch. Somatostatin strongly inhibited the basal and secretin-induced pepsin secretion. It did not, however, inhibit the secretin-induced mucus secretion, even though it decreased the basal mucus secretion. During somatostatin administration, the secretagogue effect of secretin on mucus secretion might be dissociated from its stimulatory action on pepsin secretion.

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Year:  1982        PMID: 6123137     DOI: 10.1016/0167-0115(82)90124-0

Source DB:  PubMed          Journal:  Regul Pept        ISSN: 0167-0115


  2 in total

1.  Sialic acid: ambiguous marker of pepsin-degraded mucus.

Authors:  M Guslandi
Journal:  Dig Dis Sci       Date:  1989-09       Impact factor: 3.199

2.  Pepsinogen secretion in cholecystokinin-1 receptor-deficient rats.

Authors:  Kenji Kanagawa; Hayato Nakamura; Makoto Otsuki
Journal:  Dig Dis Sci       Date:  2004-09       Impact factor: 3.199

  2 in total

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