Literature DB >> 6122578

The prevention of orchiopexy-induced testicular lesions in the pig.

M T Frankenhuis, M A Wiegerinck, M Schoorl, J Kremer, C J Wensing.   

Abstract

From previous experiments it was concluded that failure of spermatogenic cells to differentiate after orchiopexy seems to be due to surgical trauma. Furthermore it appeared that in normally descended testes of naturally unilaterally cryptorchid pigs subjected to orchiopexy, the spermatogenic epithelium was poorly developed as compared with that of scrotal testes of unilaterally cryptorchid pigs that had not undergone the surgical procedure. Even simple inguinal surgery in unilaterally naturally cryptorchid piglets may already give rise to severe histological lesions in the spermatogenic epithelium of the normally descended contralateral testes at adulthood. On the other hand extirpation of the retained testis by laparotomy does not affect the spermatogenic epithelium in the contralateral scrotal testis. From these experiments it may be concluded that with regard to the prevention of sterility in unilaterally cryptorchid pigs it may be preferable to extirpate the retained testis rather than to perform an orchiopexy.

Entities:  

Mesh:

Year:  1982        PMID: 6122578     DOI: 10.1007/bf00442323

Source DB:  PubMed          Journal:  Eur J Pediatr        ISSN: 0340-6199            Impact factor:   3.183


  7 in total

1.  STUDIES ON ARTIFICIAL CRYPTORCHIDISM: DEGENERATIVE AND REGENERATIVE CHANGES IN THE GERMINAL EPITHELIUM OF THE RAT TESTIS.

Authors:  E J CLEGG
Journal:  J Endocrinol       Date:  1963-11       Impact factor: 4.286

2.  A description of spermiogenesis in the mouse and its use in analysis of the cycle of the seminiferous epithelium and germ cell renewal.

Authors:  E F OAKBERG
Journal:  Am J Anat       Date:  1956-11

3.  Induction of spermatogenesis in the naturally cryptorchid pig.

Authors:  M T Frankenhuis; C J Wensing
Journal:  Fertil Steril       Date:  1979-04       Impact factor: 7.329

4.  [Early management of maldescended testes, based on recent biopsy results].

Authors:  W C Hecker; H A Hienz; W Mengel
Journal:  Dtsch Med Wochenschr       Date:  1972-09-08       Impact factor: 0.628

5.  The recovery of spermatogenesis in the rat testis after heat-induced degeneration.

Authors:  A W Blackshaw; P F Massey
Journal:  J Reprod Fertil       Date:  1972-01

6.  Testicular biopsy score count--a method for registration of spermatogenesis in human testes: normal values and results in 335 hypogonadal males.

Authors:  S G Johnsen
Journal:  Hormones       Date:  1970

7.  The origin of orchiopexy-induced testicular lesions in the pig.

Authors:  M T Frankenhuis; M A Wiegerinck; M Schoorl; J Kremer; C J Wensing
Journal:  Fertil Steril       Date:  1979-11       Impact factor: 7.329

  7 in total
  2 in total

1.  Fertility and unilateral undescended testis in the rat model.

Authors:  S Agarwala; D K Mitra
Journal:  Pediatr Surg Int       Date:  2013-09-21       Impact factor: 1.827

2.  High mobility group A2 (HMGA2) deficiency in pigs leads to dwarfism, abnormal fetal resource allocation, and cryptorchidism.

Authors:  Jaewook Chung; Xia Zhang; Bruce Collins; Renan B Sper; Katherine Gleason; Sean Simpson; Sehwon Koh; Jeffrey Sommer; William L Flowers; Robert M Petters; Jorge A Piedrahita
Journal:  Proc Natl Acad Sci U S A       Date:  2018-05-07       Impact factor: 11.205

  2 in total

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