Literature DB >> 6122269

Inhibition of idiotype--anti-idiotype interaction for detection of a parasite antigen: a new immunoassay.

P Potocnjak, F Zavala, R Nussenzweig, V Nussenzweig.   

Abstract

Described in this report is an immunoradiometric assay of general applicability that is based on a new principle: the inhibition of the interaction between monoclonal antibodies by an antigen. The advantages of this assay are that it measures concentrations of single epitopes, purified antigen is not required, and the reagents can be obtained in unlimited amounts and are homogeneous. Its features are particularly attractive when the antigen has not been purified and is a minor component of a complex mixture of molecule.

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Year:  1982        PMID: 6122269     DOI: 10.1126/science.6122269

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  9 in total

Review 1.  Future potential of malaria vaccines.

Authors:  M Hommel
Journal:  J R Soc Med       Date:  1989       Impact factor: 5.344

2.  [Improvement of malarial vaccines: memorandum of a USAID/WHO meeting].

Authors: 
Journal:  Bull World Health Organ       Date:  1983       Impact factor: 9.408

Review 3.  Malaria: immunity, vaccination and immunodiagnosis.

Authors:  L Perrin; A Perez; C Chizzolini
Journal:  Experientia       Date:  1984-12-15

4.  B and T cell responses elicited by monoclonal anti-idiotypic antibody (Ab2beta) mimicking gp43 from Paracoccidioides brasiliensis.

Authors:  E B Souza; J D Lopes; S R Almeida
Journal:  Clin Exp Immunol       Date:  2004-07       Impact factor: 4.330

5.  Development of malaria vaccines: memorandum from a USAID/WHO meeting.

Authors: 
Journal:  Bull World Health Organ       Date:  1983       Impact factor: 9.408

6.  Anti-idiotypic antibody as potential serodiagnostic reagent for detection of bluetongue virus infection.

Authors:  E M Zhou; W Huang
Journal:  J Clin Microbiol       Date:  1995-04       Impact factor: 5.948

7.  Anti-schistosome monoclonal antibodies of different isotypes--correlation with cytotoxicity.

Authors:  S Horowitz; R Tarrab-Hazdai; Z Eshhar; R Arnon
Journal:  EMBO J       Date:  1983       Impact factor: 11.598

Review 8.  Comprehensive Review of Human Plasmodium falciparum-Specific CD8+ T Cell Epitopes.

Authors:  Janna Heide; Kerrie C Vaughan; Alessandro Sette; Thomas Jacobs; Julian Schulze Zur Wiesch
Journal:  Front Immunol       Date:  2019-03-21       Impact factor: 7.561

9.  Rare PfCSP C-terminal antibodies induced by live sporozoite vaccination are ineffective against malaria infection.

Authors:  Stephen W Scally; Rajagopal Murugan; Alexandre Bosch; Gianna Triller; Giulia Costa; Benjamin Mordmüller; Peter G Kremsner; B Kim Lee Sim; Stephen L Hoffman; Elena A Levashina; Hedda Wardemann; Jean-Philippe Julien
Journal:  J Exp Med       Date:  2017-11-22       Impact factor: 14.307

  9 in total

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