Literature DB >> 6120843

Methamphetamine-induced depression of tryptophan hydroxylase: recovery following acute treatment.

C Bakhit, J W Gibb.   

Abstract

Acute administration of methamphetamine produced a dose-dependent depression of tryptophan hydroxylase (TPH) activity. The depression was observed in several serotonergic nerve terminal regions of the rat brain and spinal cord. Complete recovery of TPH activity following methamphetamine treatment occurred in all regions, but the time to recovery varied with the dose administered. In contrast to TPH, tyrosine hydroxylase (TH) was not affected by a single injection of methamphetamine. The data are discussed in the context of the effects of single versus repeated doses of methamphetamine on tryptophan and tyrosine hydroxylase.

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Year:  1981        PMID： 6120843     DOI： 10.1016/0014-2999(81)90505-7

Source DB:  PubMed          Journal:  Eur J Pharmacol        ISSN： 0014-2999            Impact factor:   4.432


  7 in total

1.  Loss of dopamine transporters in methamphetamine abusers recovers with protracted abstinence.

Authors:  N D Volkow; L Chang; G J Wang; J S Fowler; D Franceschi; M Sedler; S J Gatley; E Miller; R Hitzemann; Y S Ding; J Logan
Journal:  J Neurosci       Date:  2001-12-01       Impact factor: 6.167

2.  Lack of effect of kappa-opioid receptor agonism on long-term methamphetamine-induced neurotoxicity in rats.

Authors:  Kamisha L Johnson-Davis; Glen R Hanson; Kristen A Keefe
Journal:  Neurotox Res       Date:  2003       Impact factor: 3.911

3.  Role of the serotonin uptake carrier in the neurochemical response to methamphetamine: effects of citalopram and chlorimipramine.

Authors:  C J Schmidt; J W Gibb
Journal:  Neurochem Res       Date:  1985-05       Impact factor: 3.996

4.  The effects of amfonelic acid on 5-HT metabolism in rat brain.

Authors:  P C Waldmeier; A M Buchle; K Stoecklin; B Fehr; J J Feldtrauer
Journal:  J Neural Transm       Date:  1983       Impact factor: 3.575

Review 5.  Neurochemical consequences of dysphoric state during amphetamine withdrawal in animal models: a review.

Authors:  Junichi Kitanaka; Nobue Kitanaka; Motohiko Takemura
Journal:  Neurochem Res       Date:  2007-06-29       Impact factor: 3.996

6.  Congenital abnormality effect of methamphetamine on histological, cellular and chromosomal defects in fetal mice.

Authors:  Tahereh Mirjalili; Seyed Mehdi Kalantar; Maryam Shams Lahijani; Mohamad Hasan Sheikhha; Alireza Talebi
Journal:  Iran J Reprod Med       Date:  2013-01

Review 7.  Neurotoxicity of methamphetamine: Main effects and mechanisms.

Authors:  Subramaniam Jayanthi; Atul P Daiwile; Jean Lud Cadet
Journal:  Exp Neurol       Date:  2021-06-26       Impact factor: 5.620
  7 in total

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