Literature DB >> 6120169

Rapid formation of poly-gamma-glutamyl derivatives of methotrexate and their association with dihydrofolate reductase as assessed by high pressure liquid chromatography in the Ehrlich ascites tumor cell in vitro.

D W Fry, J C Yalowich, I D Goldman.   

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Year:  1982        PMID: 6120169

Source DB:  PubMed          Journal:  J Biol Chem        ISSN: 0021-9258            Impact factor:   5.157


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  34 in total

Review 1.  Pharmacogenomics in pediatric leukemia.

Authors:  Steven W Paugh; Gabriele Stocco; William E Evans
Journal:  Curr Opin Pediatr       Date:  2010-12       Impact factor: 2.856

2.  Synthesis and biological activity of a novel series of 6-substituted thieno[2,3-d]pyrimidine antifolate inhibitors of purine biosynthesis with selectivity for high affinity folate receptors over the reduced folate carrier and proton-coupled folate transporter for cellular entry.

Authors:  Yijun Deng; Xilin Zhou; Sita Kugel Desmoulin; Jianmei Wu; Christina Cherian; Zhanjun Hou; Larry H Matherly; Aleem Gangjee
Journal:  J Med Chem       Date:  2009-05-14       Impact factor: 7.446

Review 3.  Polyglutamation of methotrexate. Is methotrexate a prodrug?

Authors:  B A Chabner; C J Allegra; G A Curt; N J Clendeninn; J Baram; S Koizumi; J C Drake; J Jolivet
Journal:  J Clin Invest       Date:  1985-09       Impact factor: 14.808

4.  Formation of methotrexate polyglutamates in purified myeloid precursor cells from normal human bone marrow.

Authors:  S Koizumi; G A Curt; R L Fine; J D Griffin; B A Chabner
Journal:  J Clin Invest       Date:  1985-03       Impact factor: 14.808

Review 5.  Membrane transporters and folate homeostasis: intestinal absorption and transport into systemic compartments and tissues.

Authors:  Rongbao Zhao; Larry H Matherly; I David Goldman
Journal:  Expert Rev Mol Med       Date:  2009-01-28       Impact factor: 5.600

6.  Methotrexate Resistance in Datura innoxia (Uptake and Metabolism of Methotrexate in Wild-Type and Resistant Cell Lines).

Authors:  K. Wu; I. J. Atkinson; E. A. Cossins; J. King
Journal:  Plant Physiol       Date:  1993-02       Impact factor: 8.340

7.  Identification of the minimal functional unit of the homo-oligomeric human reduced folate carrier.

Authors:  Zhanjun Hou; Christina Cherian; Joseph Drews; Jianmei Wu; Larry H Matherly
Journal:  J Biol Chem       Date:  2009-12-17       Impact factor: 5.157

8.  Restoration of high-level transport activity by human reduced folate carrier/ThTr1 thiamine transporter chimaeras: role of the transmembrane domain 6/7 linker region in reduced folate carrier function.

Authors:  Xiang Y Liu; Teah L Witt; Larry H Matherly
Journal:  Biochem J       Date:  2003-01-01       Impact factor: 3.857

9.  Substrate-specific binding and conformational changes involving Ser313 and transmembrane domain 8 of the human reduced folate carrier, as determined by site-directed mutagenesis and protein cross-linking.

Authors:  Zhanjun Hou; Jianmei Wu; Jun Ye; Christina Cherian; Larry H Matherly
Journal:  Biochem J       Date:  2010-09-01       Impact factor: 3.857

10.  N-linked glycosylation and its impact on the electrophoretic mobility and function of the human proton-coupled folate transporter (HsPCFT).

Authors:  Ersin Selcuk Unal; Rongbao Zhao; Andong Qiu; I David Goldman
Journal:  Biochim Biophys Acta       Date:  2008-03-20
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