Literature DB >> 61192

The effect of EDTA and metal cations on the 5-bromoindoxyl acetate esterase activity in the thyroid of the guinea pig.

S Kirkeby.   

Abstract

Miscellaneous metal cations and EDTA have been used as activators and inhibitors of esterase activity in the thyroid of the guinea-pig. The results indicate that the 5-bromoiondoxyl acetate esterase in the epithelial cells probably consists of two different A-esterase isoenzymes, one present in group I cells (the para-, intra-, and inter-follicular cells) and the other in group II cells (the follicular cells proper). The first isoenzyme seems to be calcium-dependent whereas the other is activated by various metal ions. Ca2+ + Mn2+ and Ca2+ + Co2+ were found to activate the esterase activity in group I cells. EDTA and Mn2+, on the other hand, activated the esterase activity in group II cells.

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Year:  1976        PMID： 61192     DOI： 10.1007/bf01003836

Source DB:  PubMed          Journal:  Histochem J        ISSN： 0018-2214


  9 in total

1.  Curtain electrophoretic separation of phenyl acetate hydrolysing esterases of human serum. Demonstration of an EDTA-dependent enzyme.

Authors:  B BJORKLUND; J E PAULSSON; S EKBERG
Journal:  Proc Soc Exp Biol Med       Date:  1962-07

2.  Arylesterases in blood: effect of calcium and inhibitors.

Authors:  E G ERDOS; C R DEBAY; M P WESTERMAN
Journal:  Biochem Pharmacol       Date:  1960-11       Impact factor: 5.858

3.  Activation and inhibition of the arylesterase of human serum.

Authors:  E G ERDOS; C R DEBAY; M P WESTERMAN
Journal:  Nature       Date:  1959-08-08       Impact factor: 49.962

4.  The differentiation of the A-type esterases in sheep serum.

Authors:  A R MAIN
Journal:  Biochem J       Date:  1960-04       Impact factor: 3.857

5.  Studies in enzyme cytochemistry. V. An appraisal of indigogenic reactions for esterase localization.

Authors:  S J HOLT; R F WITHERS
Journal:  Proc R Soc Lond B Biol Sci       Date:  1958-04-08

6.  Dialkylfluorophosphatase of kidney. I. Purification and properties.

Authors:  L A MOUNTER; C S FLOYD; A CHANUTIN
Journal:  J Biol Chem       Date:  1953-09       Impact factor: 5.157

7.  Interaction between aromatic esterase of human serum and bivalent metal ions.

Authors:  A V MARTON; W KALOW
Journal:  Can J Biochem Physiol       Date:  1962-03

8.  Carboxylic ester hydrolases in the thyroid gland of the guinea-pig. A light microscopic study.

Authors:  S Kirkeby
Journal:  Histochem J       Date:  1976-01

9.  The activity of non-specific esterase in the thyroid epithelial cells of the guinea pig as influenced by various inhibitors and activators. A histochemical study.

Authors:  S Kirkeby
Journal:  Histochemistry       Date:  1976-07-30
  9 in total
  1 in total

1.  SH groups in the alpha-naphthyl acetate esterase in the thyroid of the guinea-pig. A histochemical study.

Authors:  S Kirkeby
Journal:  Histochemistry       Date:  1976-10-22
  1 in total

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