Literature DB >> 6118859

A double-blind controlled trial of the effect of sodium cromoglycate in preventing relapse in ulcerative colitis.

P J Whorwell, G M Whorwell, J Bamforth, D Colin Jones, P Down, A Edwards, A E Gent, P Golding, K R Gough, M D Hellier, P Isaacson, C A Loehry, G J Milton-Thompson, C L Smith, R P Waldram, R Wright.   

Abstract

A double-blind controlled trial of the effect of sodium cromoglycate (SCG) in preventing relapse in ulcerative colitis has been completed in 100 subjects. In patients already taking sulphasalazine, SCG did not prove to be of any additional benefit. However, in patients not on any other maintenance therapy, the relapse rate was 40% for SCG as compared with 75% for placebo. A large study of the effect of SCG in patients intolerant of sulphasalazine is indicated.

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Year:  1981        PMID: 6118859      PMCID: PMC2424968          DOI: 10.1136/pgmj.57.669.436

Source DB:  PubMed          Journal:  Postgrad Med J        ISSN: 0032-5473            Impact factor:   2.401


  7 in total

1.  Controlled trial of disodium cromoglycate in chronic persistent ulcerative colitis.

Authors:  N A Buckell; S R Gould; D W Day; J E Lennard-Jones; A M Edwards
Journal:  Gut       Date:  1978-12       Impact factor: 23.059

2.  Treatment of ulcerative colitis with oral disodium cromoglycate. A double-blind controlled trial.

Authors:  V Mani; G Lloyd; F H Green; H Fox; L A Turnberg
Journal:  Lancet       Date:  1976-02-28       Impact factor: 79.321

3.  Comparative trial of sulphasalazine and oral sodium cromoglycate in the maintenance of remission in ulcerative colitis.

Authors:  M W Dronfield; M J Langman
Journal:  Gut       Date:  1978-12       Impact factor: 23.059

4.  Disodium cromoglycate in the treatment of chronic proctitis.

Authors:  R V Heatley; B J Calcraft; J Rhodes; E Owen; B K Evans
Journal:  Gut       Date:  1975-07       Impact factor: 23.059

5.  A controlled therapeutic trial of long-term maintenance treatment of ulcerative colitis with sulphazalazine (Salazopyrin).

Authors:  A S Dissanayake; S C Truelove
Journal:  Gut       Date:  1973-12       Impact factor: 23.059

6.  Comparison of disodium cromoglycate and sulphasalazine as maintenance therapy for ulcerative colitis.

Authors:  C P Willoughby; M F Heyworth; J Piris; S C Truelove
Journal:  Lancet       Date:  1979-01-20       Impact factor: 79.321

7.  Optimum dose of sulphasalazine for maintenance treatment in ulcerative colitis.

Authors:  A K Azad Khan; D T Howes; J Piris; S C Truelove
Journal:  Gut       Date:  1980-03       Impact factor: 23.059

  7 in total
  5 in total

1.  Meta-analysis of the placebo response in ulcerative colitis.

Authors:  Sagar Garud; Alphonso Brown; Adam Cheifetz; Emily B Levitan; Ciaran P Kelly
Journal:  Dig Dis Sci       Date:  2007-10-13       Impact factor: 3.199

2.  Sodium cromoglycate in proctitis and ulcerative colitis.

Authors:  R N Allan
Journal:  Br Med J (Clin Res Ed)       Date:  1982-01-09

3.  Colonic mucosal mast cell distribution at line of demarcation of active ulcerative colitis.

Authors:  T King; W Biddle; P Bhatia; J Moore; P B Miner
Journal:  Dig Dis Sci       Date:  1992-04       Impact factor: 3.199

Review 4.  Non-pulmonary allergic diseases and inflammatory bowel disease: a qualitative review.

Authors:  David S Kotlyar; Mili Shum; Jennifer Hsieh; Wojciech Blonski; David A Greenwald
Journal:  World J Gastroenterol       Date:  2014-08-28       Impact factor: 5.742

5.  Combination therapy using fexofenadine, disodium cromoglycate, and a hypoallergenic amino acid-based formula induced remission in a patient with steroid-dependent, chronically active ulcerative colitis.

Authors:  M Raithel; S Winterkamp; M Weidenhiller; S Müller; E G Hahn
Journal:  Int J Colorectal Dis       Date:  2006-03-31       Impact factor: 2.796

  5 in total

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