Literature DB >> 6118824

The stimulation of ion fluxes in brain slices by glutamate and other excitatory amino acids.

V I Teichberg, O Goldberg, A Luini.   

Abstract

The stimulation of ion movements by excitatory amino acids in brain slices allows the study of various events related to the process of excitatory neurotransmission. Presynaptic mechanisms of uptake of putative neurotransmitters can be followed by the influx of Na+ ions. Postsynaptic depolarizations due to the activation of action potentials or of ionophores associated with specific receptors can be monitored by measurements of the rate of efflux of radioactive tracer ions. Thus, the pharmacological properties of the excitatory amino acid receptors can be investigated as well as those of their putative endogenous effectors.

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Year:  1981        PMID： 6118824     DOI： 10.1007/bf00232580

Source DB:  PubMed          Journal:  Mol Cell Biochem        ISSN： 0300-8177            Impact factor:   3.396


  52 in total

Review 1.  Cyclic nucleotides and nervous system function.

Authors:  J A Nathanson
Journal:  Physiol Rev       Date:  1977-04       Impact factor: 37.312

2.  Structural requirements for the inhibition for L-glutamate uptake by glia and nerve endings.

Authors:  P J Roberts; J C Watkins
Journal:  Brain Res       Date:  1975-02-21       Impact factor: 3.252

3.  A glutamatergic corticostriatal path?

Authors:  P L McGeer; E G McGeer; U Scherer; K Singh
Journal:  Brain Res       Date:  1977-06-10       Impact factor: 3.252

4.  Evaluation of the selectivity of antagonists of glutamate and acetylcholine applied microiontophoretically onto cortical neurones.

Authors:  G Clarke; D W Straughan
Journal:  Neuropharmacology       Date:  1977-06       Impact factor: 5.250

5.  Mouse spinal cord in cell culture. III. Neuronal chemosensitivity and its relationship to synaptic activity.

Authors:  B R Ransom; P N Bullock; P G Nelson
Journal:  J Neurophysiol       Date:  1977-09       Impact factor: 2.714

6.  Tetrodotoxin on the sodium and other ions of cerebral tissues, excited electrically and with glutamate.

Authors:  H McIlwain; J A Harvery; G Rodriguez
Journal:  J Neurochem       Date:  1969-03       Impact factor: 5.372

7.  Action of the neurotoxin kainic acid on high affinity uptake of L-glutamic acid in rat brain slices.

Authors:  G A Johnston; S M Kennedy; B Twitchin
Journal:  J Neurochem       Date:  1979-01       Impact factor: 5.372

Review 8.  Possible role for cyclic nucleotides and phosphorylated membrane proteins in postsynaptic actions of neurotransmitters.

Authors:  P Greengard
Journal:  Nature       Date:  1976-03-11       Impact factor: 49.962

9.  Excitatory acidic amino acids and the cation content and sodium ion flux of isolated tissues from the brain.

Authors:  J A Harvey; H McIlwain
Journal:  Biochem J       Date:  1968-06       Impact factor: 3.857

10.  Cooperative activation of action potential Na+ ionophore by neurotoxins.

Authors:  W A Catterall
Journal:  Proc Natl Acad Sci U S A       Date:  1975-05       Impact factor: 11.205
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  2 in total

1.  Cellular uptake disguises action of L-glutamate on N-methyl-D-aspartate receptors. With an appendix: diffusion of transported amino acids into brain slices.

Authors:  J Garthwaite
Journal:  Br J Pharmacol       Date:  1985-05       Impact factor: 8.739

2.  Effects of excitatory amino acids and their antagonists on membrane and action potentials of cat caudate neurones.

Authors:  P L Herrling; R Morris; T E Salt
Journal:  J Physiol       Date:  1983-06       Impact factor: 5.182
  2 in total

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