| Literature DB >> 6118426 |
J H Jonkman, H G Westenberg, E Van Der Kleyn.
Abstract
Plasma concentration-time curves are described for the intravenous infusion and portal vein infusion of the quaternary ammonium compound thiazinamium methylsulfate to dogs. Comparison of areas under the curve indicate that hepatic first-pass elimination occurred on the order of 25--50%.Entities:
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Year: 1981 PMID: 6118426 DOI: 10.1002/jps.2600700831
Source DB: PubMed Journal: J Pharm Sci ISSN: 0022-3549 Impact factor: 3.534