Literature DB >> 6116524

Influence of cholinomimetics and cholinolytics on vestibular compensation.

W Abeln, H Bienhold, H Flohr.   

Abstract

The influence of cholinomimetics and cholinolytics on vestibular compensation was investigated in Rana temporaria. In compensated animals cholinomimetics induced a complete decompensation with reappearance of all symptoms characteristic of the precompensated state. Cholinolytic exerted antagonistic effects. They induced postural and locomotor symptoms which were a mirror-image of those observed in the precompensated state. The findings support the assumption that the compensatory reorganization of the vestibular system involves the modification of cholinergic brain stem synapses.

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Year:  1981        PMID： 6116524     DOI： 10.1016/0006-8993(81)91055-6

Source DB:  PubMed          Journal:  Brain Res        ISSN： 0006-8993            Impact factor:   3.252


  4 in total

1.  Characterizing high-velocity angular vestibulo-ocular reflex function in service members post-blast exposure.

Authors:  Matthew R Scherer; Mark J Shelhamer; Michael C Schubert
Journal:  Exp Brain Res       Date:  2010-11-27       Impact factor: 1.972

2.  Neurochemical changes in the cholinergic system of the rat lateral vestibular nucleus following hemilabyrinthectomy.

Authors:  C Yamada; M Tachibana; K Kuriyama
Journal:  Arch Otorhinolaryngol       Date:  1988

Review 3.  Antivertigo medications and drug-induced vertigo. A pharmacological review.

Authors:  O Rascol; T C Hain; C Brefel; M Benazet; M Clanet; J L Montastruc
Journal:  Drugs       Date:  1995-11       Impact factor: 9.546

4.  Muscarinic and gamma-aminobutyric acid-ergic receptor changes during vestibular compensation. A quantitative autoradiographic study of the vestibular nuclei complex in the rat.

Authors:  L Calzà; L Giardino; M Zanni; G Galetti
Journal:  Eur Arch Otorhinolaryngol       Date:  1992       Impact factor: 2.503
  4 in total

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