| Literature DB >> 6116215 |
W Kromer, V Höllt, H Schmidt, A Herz.
Abstract
The guinea-pig small intestine contains high amounts of immunoreactive dynorphin (9 pmol/g), which is released from the in vitro preparation under resting conditions (basal release). Initiation of peristaltic activity by distension of the intestinal wall via sustained elevated intraluminal pressure lowers the levels of immunoreactive dynorphin in the bathing solution (by more than 60%). The present data are suggestive of a role of this endogenous opioid peptide in the control of intestinal peristalsis.Entities:
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Year: 1981 PMID： 6116215 DOI： 10.1016/0304-3940(81)90100-2
Source DB: PubMed Journal: Neurosci Lett ISSN： 0304-3940 Impact factor: 3.046