Literature DB >> 6115734

Human xylazine overdose: a comparative review with clonidine, phenothiazines, and tricyclic antidepressants.

A G Gallanosa, D A Spyker, J R Shipe, D L Morris.   

Abstract

We report a case of horse tranquilizer (xylazine) overdose from oral ingestion in man, detail a gas-liquid chromatography/mass spectrometer method for xylazine assay in the blood and urine, and suggest the management of acute poisoning. We present a comparative review of some toxicological properties that xylazine shares with the pharmacologically related clonidine and with the structurally related phenothiazines and the tricyclic antidepressants.

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Year:  1981        PMID： 6115734     DOI： 10.3109/15563658108990293

Source DB:  PubMed          Journal:  Clin Toxicol        ISSN： 0009-9309            Impact factor:   4.467


  8 in total

Review 1.  Comprehensive review of cardiovascular toxicity of drugs and related agents.

Authors:  Přemysl Mladěnka; Lenka Applová; Jiří Patočka; Vera Marisa Costa; Fernando Remiao; Jana Pourová; Aleš Mladěnka; Jana Karlíčková; Luděk Jahodář; Marie Vopršalová; Kurt J Varner; Martin Štěrba
Journal:  Med Res Rev       Date:  2018-01-05       Impact factor: 12.944

2.  The emerging of xylazine as a new drug of abuse and its health consequences among drug users in Puerto Rico.

Authors:  J C Reyes; J L Negrón; H M Colón; A M Padilla; M Y Millán; T D Matos; R R Robles
Journal:  J Urban Health       Date:  2012-06       Impact factor: 3.671

3.  Toxic effects of xylazine on endothelial cells in combination with cocaine and 6-monoacetylmorphine.

Authors:  L A Silva-Torres; C Vélez; J Lyvia Alvarez; J G Ortiz; B Zayas
Journal:  Toxicol In Vitro       Date:  2014-07-08       Impact factor: 3.500

4.  Accidental self administration of xylazine in a veterinary nurse.

Authors:  A Samanta; C Roffe; K L Woods
Journal:  Postgrad Med J       Date:  1990-03       Impact factor: 2.401

5.  Effects of combined ketamine/xylazine anesthesia on light induced retinal degeneration in rats.

Authors:  Blanca Arango-Gonzalez; Andreas Schatz; Sylvia Bolz; Javier Eslava-Schmalbach; Gabriel Willmann; Ahmad Zhour; Eberhart Zrenner; M Dominik Fischer; Florian Gekeler
Journal:  PLoS One       Date:  2012-04-25       Impact factor: 3.240

6.  Xylazine as a drug of abuse and its effects on the generation of reactive species and DNA damage on human umbilical vein endothelial cells.

Authors:  Luz Silva-Torres; Christian Veléz; Lyvia Alvarez; Beatriz Zayas
Journal:  J Toxicol       Date:  2014-11-11

7.  Nanocoral-like Polyaniline-Modified Graphene-Based Electrochemical Paper-Based Analytical Device for a Portable Electrochemical Sensor for Xylazine Detection.

Authors:  Kasrin Saisahas; Asamee Soleh; Kiattisak Promsuwan; Jenjira Saichanapan; Apichai Phonchai; Nabeesathul Sumayya Mohamed Sadiq; Way Koon Teoh; Kah Haw Chang; Ahmad Fahmi Lim Abdullah; Warakorn Limbut
Journal:  ACS Omega       Date:  2022-04-12

8.  Xylazine-induced reduction of tissue sensitivity to insulin leads to acute hyperglycemia in diabetic and normoglycemic monkeys.

Authors:  Yong-Fu Xiao; Bingdi Wang; Xiaoli Wang; Fenglai Du; Michael Benzinou; Yi-Xin Jim Wang
Journal:  BMC Anesthesiol       Date:  2013-10-20       Impact factor: 2.217
  8 in total

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