Literature DB >> 6114722

The importance of human intestinal diamine oxidase in the oxidation of histamine and/or putrescine.

T Biegański, J Kusche, K D Feussner, R Hesterberg, H Richter, W Lorenz.   

Abstract

Histamine, naturally methylated histamine and putrescine are good substrates for human intestinal diamine oxidase, N-Methyl-N-formylhydrazine, the constituent of the mashroom poison-gyromitrin is an inhibitor of human intestinal diamine oxidase. Burimamide inhibits more effectively mammalian intestinal diamine oxidases than pea seedling diamine oxidase, beta-aminopropionitrile is a better inhibitor of pea seedling enzyme than mammalian diamine oxidases. This inhibitory differences might be related to preference in histamine or putrescine oxidizing activity of these enzymes.

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Year:  1980        PMID: 6114722

Source DB:  PubMed          Journal:  Arch Immunol Ther Exp (Warsz)        ISSN: 0004-069X            Impact factor:   4.291


  3 in total

1.  N-methyl-N-formylhydrazine: a toxic and mutagenic inhibitor of the intestinal diamine oxidase.

Authors:  T Biegański; R Braun; J Kusche
Journal:  Agents Actions       Date:  1984-04

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Authors:  Tamara Searle; Faisal R Ali; Sarah Carolides; Firas Al-Niaimi
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3.  Why Monoamine Oxidase B Preferably Metabolizes N-Methylhistamine over Histamine: Evidence from the Multiscale Simulation of the Rate-Limiting Step.

Authors:  Aleksandra Maršavelski; Janez Mavri; Robert Vianello; Jernej Stare
Journal:  Int J Mol Sci       Date:  2022-02-08       Impact factor: 5.923

  3 in total

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