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Literature DB >> 6113751

Viruses as nonspecific modulators of immunological reactivity.

Abstract

As shown experimentally and by examination of patients, numerous DNA and RNA viruses induce transitory nonspecific changes in the immune response of the host to heterologous antigens. Attenuation does not affect this property of the parent strains. Nonspecific immunomodulation is connected with disturbed functions of B and T lymphocytes, macrophages and haemopoietic cells. The actual mechanisms of immunomodulation differ in different infections.

Entities: Disease Species

Mesh：

Year: 1981 PMID： 6113751

Source DB: PubMed Journal: Acta Virol ISSN： 0001-723X Impact factor: 1.162

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Cited

10 in total

1. Characterization of a murine cytomegalovirus-induced immunosuppressive factor.

Authors: P F Whyte; R Subramaniam; J B Hudson
Journal: Arch Virol Date: 1987 Impact factor: 2.574

2. The decreased antibacterial activity of oral polymorphonuclear leukocytes coincides with the occurrence of virus-carrying oral lymphocytes and epithelial cells.

Authors: J Ongrádi; K Sallay; G Kulcsár
Journal: Folia Microbiol (Praha) Date: 1987 Impact factor: 2.099

3. Suppression of contact sensitivity by a plastic adherent T-cell, induced in mice infected with Newcastle disease virus (NDV).

Authors: D Lio; F Dieli; E Cillari; A Salerno
Journal: Br J Exp Pathol Date: 1987-10

4. Generation in vitro of alloreactive lymphocytes is suppressed by the addition of spleen cells from mice infected with lymphocytic choriomeningitis virus.

Authors: M Varho-Göbel; G Wolff; W Slenczka
Journal: Med Microbiol Immunol Date: 1986 Impact factor: 3.402

Viruses as nonspecific modulators of immunological reactivity.

1. Characterization of a murine cytomegalovirus-induced immunosuppressive factor.

2. The decreased antibacterial activity of oral polymorphonuclear leukocytes coincides with the occurrence of virus-carrying oral lymphocytes and epithelial cells.

3. Suppression of contact sensitivity by a plastic adherent T-cell, induced in mice infected with Newcastle disease virus (NDV).

4. Generation in vitro of alloreactive lymphocytes is suppressed by the addition of spleen cells from mice infected with lymphocytic choriomeningitis virus.

5. Anomalous antibody responses in viral infection: specific stimulation or polyclonal activation?

6. Induction and Ly phenotype of suppressor T cells in mice during primary infection with dengue virus.

7. Influenza viruses are T cell-independent B cell mitogens.

8. Mitogenic activity of Sindbis virus and its isolated glycoproteins.

9. Suppressor T-cell population induced by Junin virus in adult mice.

Review 10. Animal viruses of economic importance: genetic variation, persistence, and prospects for their control.