Literature DB >> 6112275

Prospective study of liver function following repeat halothane and enflurane.

J W Dundee, P D McIlroy, J P Fee, G W Black.   

Abstract

In a prospective study of liver function following repeat anaesthesia, patients who received repeat halothane had a higher frequency of abnormal liver enzyme results than a similar group who received repeat enflurane. Obesity and short intervals between administrations increased the likelihood of abnormal liver enzyme activity in the halothane group. Enflurane would seem to be the volatile agent of choice for repeat anaesthesia in such circumstances.

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Year:  1981        PMID: 6112275      PMCID: PMC1438394          DOI: 10.1177/014107688107400410

Source DB:  PubMed          Journal:  J R Soc Med        ISSN: 0141-0768            Impact factor:   18.000


  14 in total

1.  Unexplained postoperative fever. Its value as a sign of halothane sensitization.

Authors:  M H Dykes
Journal:  JAMA       Date:  1971-04-26       Impact factor: 56.272

2.  Is halothane hepatitis chronic active hepatitis?

Authors:  M H Dykes
Journal:  Anesthesiology       Date:  1977-04       Impact factor: 7.892

Review 3.  Halothane hepatitis: what's new?

Authors:  M J Cousins
Journal:  Drugs       Date:  1980-01       Impact factor: 9.546

4.  Toxicity of halogenated volatile anesthetics in isolated rat hepatocytes.

Authors:  N H Stacey; B G Priestly; R C Hall
Journal:  Anesthesiology       Date:  1978-01       Impact factor: 7.892

5.  A prospective study of hepatocellular function after repeated exposures to halothane or enflurane in women undergoing radium therapy for cervical cancer.

Authors:  P J Allen; J W Downing
Journal:  Br J Anaesth       Date:  1977-10       Impact factor: 9.166

6.  Unexplained hepatitis following halothane.

Authors:  B Walton; B R Simpson; L Strunin; D Doniach; J Perrin; A J Appleyard
Journal:  Br Med J       Date:  1976-05-15

7.  Halothane-related hepatitis. A clinical study of twenty-six cases.

Authors:  P J Moult; S Sherlock
Journal:  Q J Med       Date:  1975-01

8.  Volatile metabolites and decomposition products of halothane in man.

Authors:  J H Sharp; J R Trudell; E N Cohen
Journal:  Anesthesiology       Date:  1979-01       Impact factor: 7.892

9.  Controlled trial of repeated halothane anaesthetics in patients with carcinoma of the uterine cervix treated with radium.

Authors:  J Trowell; R Peto; A C Smith
Journal:  Lancet       Date:  1975-04-12       Impact factor: 79.321

10.  Controlled prospective study of the effect on liver function of multiple exposures to halothane.

Authors:  R Wright; O E Eade; M Chisholm; M Hawksley; B Lloyd; T M Moles; J C Edwards; M J GArdner
Journal:  Lancet       Date:  1975-04-12       Impact factor: 79.321

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  2 in total

1.  Halothane related liver affection in an anaesthetist.

Authors:  S Lings
Journal:  Br J Ind Med       Date:  1988-10

Review 2.  Comparative tolerability profiles of the inhaled anaesthetics.

Authors:  J P Fee; G H Thompson
Journal:  Drug Saf       Date:  1997-03       Impact factor: 5.606

  2 in total

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