Literature DB >> 6111672

Prostacyclin administration during cardiopulmonary bypass in man.

D B Longmore, J G Bennett, P M Hoyle, M A Smith, A Gregory, T Osivand, W A Jones.   

Abstract

In a double-blind trial prostacyclin was given to 12 of 23 patients undergoing coronary vein grafting. The treatment group showed a preservation of platelet number and function, with a halving of blood loss in the first 18 h postoperatively. The heparin sparing effect of prostacyclin was confirmed, as were the vasodilator effects which were not troublesome.

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Year:  1981        PMID: 6111672     DOI: 10.1016/s0140-6736(81)92680-5

Source DB:  PubMed          Journal:  Lancet        ISSN: 0140-6736            Impact factor:   79.321


  15 in total

1.  Quantification of extracorporeal platelet deposition in cardiopulmonary bypass: effects of ZK 36374, a prostacyclin analogue.

Authors:  W Martin; T Spyt; I Thomas; J F Davidson; D J Wheatley
Journal:  Eur J Nucl Med       Date:  1989

2.  Effects of taprostene, a stable prostacyclin analogue, on haemodynamics, platelet function and arachidonate metabolism in healthy volunteers.

Authors:  I Virgolini; P Fitscha; H Sinzinger; H Barth
Journal:  Eur J Clin Pharmacol       Date:  1990       Impact factor: 2.953

Review 3.  Prostaglandins and anaesthesia.

Authors:  C H Kehler
Journal:  Can Anaesth Soc J       Date:  1983-05

Review 4.  Nobel lecture, 8th December 1982. Adventures and excursions in bioassay: the stepping stones to prostacyclin.

Authors:  J R Vane
Journal:  Br J Pharmacol       Date:  1983-08       Impact factor: 8.739

Review 5.  Nobel lecture. Adventures and excursions in bioassay--the stepping stones to prostacyclin.

Authors:  J R Vane
Journal:  Postgrad Med J       Date:  1983-12       Impact factor: 2.401

Review 6.  Prostaglandins and the cardiovascular system.

Authors:  J R Vane
Journal:  Br Heart J       Date:  1983-05

7.  The effect of prostacyclin on cerebral vasospasm. An experimental study.

Authors:  L Quintana; R Konda; Y Ishibashi; T Yoshimoto; J Suzuki
Journal:  Acta Neurochir (Wien)       Date:  1982       Impact factor: 2.216

8.  Low-dose Iloprost infusion improves insulin action and non-oxidative glucose metabolism in hypertensive patients.

Authors:  G Paolisso; A Gambardella; F Saccomanno; G Varricchio; A D'Amore; M Varricchio
Journal:  Eur J Clin Pharmacol       Date:  1995       Impact factor: 2.953

9.  Effect of prostacyclin (PGI2) on water and solute transport in the human jejunum.

Authors:  K J Moriarty; J O'Grady; D D Rolston; M J Kelly; M L Clark
Journal:  Gut       Date:  1986-02       Impact factor: 23.059

10.  A prospective study of the clinical benefits of prostacyclin in 554 cardiopulmonary bypass procedures.

Authors:  M Merli; B Amari; C Cattani; L Villa; M M Visigalli; A Pellegrini
Journal:  Tex Heart Inst J       Date:  1988
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