Literature DB >> 6111447

Isolation and characterization of rat hypothalamic somatostatin-14.

P Bohlen, R Benoit, N Ling, R Guillemin, P Brazeau.   

Abstract

A peptide with somatostatin-like immuno- and bioactivity has been isolated from 1165 rat hypothalami by using antisomatostatin affinity chromatography, gel filtration and reverse-phase high-performance liquid chromatography. The isolated peptide is indistinguishable from synthetic somatostatin-14 with respect to chromatographic properties and amino acid composition. We therefore propose that rat hypothalamic somatostatin-14 is identical in structure to somatostatin-14 found in other species.

Entities:  

Mesh：

Substances：

Year:  1981        PMID： 6111447     DOI： 10.1210/endo-108-5-2008

Source DB:  PubMed          Journal:  Endocrinology        ISSN： 0013-7227            Impact factor:   4.736


  4 in total

1.  Structure-activity relationships of somatostatin analogs in the rabbit ileum and the rat colon.

Authors:  L E Rosenthal; D J Yamashiro; J Rivier; W Vale; M Brown; K Dharmsathaphorn
Journal:  J Clin Invest       Date:  1983-04       Impact factor: 14.808

2.  Presence of somatostatin-28-(1-12) in hypothalamus and pancreas.

Authors:  R Benoit; P Böhlen; N Ling; A Briskin; F Esch; P Brazeau; S Y Ying; R Guillemin
Journal:  Proc Natl Acad Sci U S A       Date:  1982-02       Impact factor: 11.205

3.  Serotonin-, somatostatin- and chromogranin A-containing cells of the urethro-prostatic complex in the sheep. An immunocytochemical and immunofluorescent study.

Authors:  A Vittoria; E La Mura; T Cocca; A Cecio
Journal:  J Anat       Date:  1990-08       Impact factor: 2.610

4.  Biosynthesis of immunoreactive somatostatin by hypothalamic neurons in culture.

Authors:  H H Zingg; Y C Patel
Journal:  J Clin Invest       Date:  1982-11       Impact factor: 14.808
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.