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Literature DB >> 6107498

Diminished bacterial defences with intralipid.

G W Fischer, K W Hunter, S R Wilson, A D Mease.

Abstract

'Intralipid', a lipid emulsion used in parenteral nutrition, impaired bacterial clearance and enhanced bacterial virulence in mice. In addition it inhibited the chemotaxis of human neutrophils in vitro. Intralipid may enhance the risk of bacterial sepsis in certain patients.

Entities: Chemical Disease Species

Mesh：

Substances：

Year: 1980 PMID： 6107498 DOI： 10.1016/s0140-6736(80)90171-3

Source DB: PubMed Journal: Lancet ISSN： 0140-6736 Impact factor: 79.321

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Cited

26 in total

1. Bactericidal activity against coagulase-negative staphylococci is impaired in infants receiving long-term parenteral nutrition.

Authors: Y Okada; N J Klein; H K van Saene; G Webb; H Holzel; A Pierro
Journal: Ann Surg Date: 2000-02 Impact factor: 12.969

2. Hemoglobin-vesicles as oxygen carriers: influence on phagocytic activity and histopathological changes in reticuloendothelial system.

Authors: H Sakai; H Horinouchi; K Tomiyama; E Ikeda; S Takeoka; K Kobayashi; E Tsuchida
Journal: Am J Pathol Date: 2001-09 Impact factor: 4.307

10. Impaired splenic function and tuftsin deficiency in patients with intestinal failure on long term intravenous nutrition.

Authors: G Zoli; G R Corazza; S Wood; R Bartoli; G Gasbarrini; M J Farthing
Journal: Gut Date: 1998-12 Impact factor: 23.059

Diminished bacterial defences with intralipid.

1. Bactericidal activity against coagulase-negative staphylococci is impaired in infants receiving long-term parenteral nutrition.

2. Hemoglobin-vesicles as oxygen carriers: influence on phagocytic activity and histopathological changes in reticuloendothelial system.

3. Splenic macrophages in preterm infants: a necropsy study.

4. Further characterization of the impaired protective function in mice fed with lipid diet.

5. Bowel rest and nutritional support in the management of Crohn's disease.

Review 6. Modulation of immune cell function by polyunsaturated fatty acids.

Review 7. Pathogenesis of infections related to intravascular catheterization.

8. Clinical and metabolic consequences of two regimens of total parenteral nutrition in the newborn.

9. Intralipid alters macrophage membrane fatty acid composition and inhibits complement (C2) synthesis.

10. Impaired splenic function and tuftsin deficiency in patients with intestinal failure on long term intravenous nutrition.