Literature DB >> 6107453

Raised cytomegalovirus-antibody level in cerebrospinal fluid of schizophrenic patients.

P Albrecht, E F Torrey, E Boone, J T Hicks, N Daniel.   

Abstract

The serum and cerebrospinal fluid (CSF) of 60 schizophrenic patients and 26 controls were analysed for viral antibody against cytomegalovirus (CMV), vaccinia virus, herpes simplex virus type 1 (HSV), and type A influenza virus. A CSF/serum antibody ratio more than 2 standard deviations above the mean of the controls suggested local antibody production in the central nervous system. 68% of the patients had an increased CSF/serum antibody ratio for CMV antibody, 14% for vaccinia antibody, 4% for HSV antibody, and 15% for influenza virus antibody.

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Year:  1980        PMID： 6107453     DOI： 10.1016/s0140-6736(80)90386-4

Source DB:  PubMed          Journal:  Lancet        ISSN： 0140-6736            Impact factor:   79.321


  14 in total

Review 1.  Cerebrospinal fluid biomarker candidates of schizophrenia: where do we stand?

Authors:  Nenad Vasic; Bernhard J Connemann; Robert C Wolf; Hayrettin Tumani; Johannes Brettschneider
Journal:  Eur Arch Psychiatry Clin Neurosci       Date:  2011-12-16       Impact factor: 5.270

2.  Search for viral nucleic acid sequences in the post mortem brains of patients with schizophrenia and individuals who have committed suicide.

Authors:  G I Carter; G R Taylor; T J Crow
Journal:  J Neurol Neurosurg Psychiatry       Date:  1987-03       Impact factor: 10.154

Review 3.  Cytomegalovirus and schizophrenia.

Authors:  E Fuller Torrey; Markus F Leweke; Markus J Schwarz; Norbert Mueller; Silke Bachmann; Johannes Schroeder; Faith Dickerson; Robert H Yolken
Journal:  CNS Drugs       Date:  2006       Impact factor: 5.749

Review 4.  The biology of schizophrenia.

Authors:  T J Crow
Journal:  Experientia       Date:  1982-11-15

Review 5.  Immunological aetiology of major psychiatric disorders: evidence and therapeutic implications.

Authors:  Barbara Sperner-Unterweger
Journal:  Drugs       Date:  2005       Impact factor: 9.546

Review 6.  Viruses, schizophrenia, and bipolar disorder.

Authors:  R H Yolken; E F Torrey
Journal:  Clin Microbiol Rev       Date:  1995-01       Impact factor: 26.132

Review 7.  The human endogenous retrovirus link between genes and environment in multiple sclerosis and in multifactorial diseases associating neuroinflammation.

Authors:  Hervé Perron; Alois Lang
Journal:  Clin Rev Allergy Immunol       Date:  2010-08       Impact factor: 8.667

8.  Evaluation of HLA polymorphisms in relation to schizophrenia risk and infectious exposure.

Authors:  Mikhil Bamne; Joel Wood; Kodavali Chowdari; Annie M Watson; Cemil Celik; Hader Mansour; Lambertus Klei; Ruben C Gur; L DiAnne Bradford; Monica E Calkins; Alberto B Santos; Neil Edwards; Joseph Kwentus; Joseph P McEvoy; Trina B Allen; Robert M Savage; Henry A Nasrallah; Raquel E Gur; Rodney T Perry; Rodney C P Go; Bernie Devlin; Robert Yolken; Vishwajit L Nimgaonkar
Journal:  Schizophr Bull       Date:  2012-09-10       Impact factor: 9.306

9.  Human cytomegalovirus DNA in the temporal cortex of a schizophrenic patient.

Authors:  H W Moises; R Rüger; G P Reynolds; B Fleckenstein
Journal:  Eur Arch Psychiatry Neurol Sci       Date:  1988

10.  Detection and sequence analysis of borna disease virus p24 RNA from peripheral blood mononuclear cells of patients with mood disorders or schizophrenia and of blood donors.

Authors:  Y Iwata; K Takahashi; X Peng; K Fukuda; K Ohno; T Ogawa; K Gonda; N Mori; S Niwa; S Shigeta
Journal:  J Virol       Date:  1998-12       Impact factor: 5.103
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