Literature DB >> 6106663

Effects of acute and chronic administration of phencyclidine on tyrosine hydroxylase activity in rat striatum.

R C Smith, D Taylor, B T Ho, D E Leelavathi.   

Abstract

Following a single dose of phencyclidine (PCP) striatal tyrosine hydroxylase (TH) activity was decreased 42% 15 min after PCP administration, but returned toward baseline levels by 45 min post-drug. Twenty-four hours after the 30th dose of PCP, TH activity remained depressed when compared to the chronic slaine controls. TH activity was not further depressed 15 or 45 min after the 31st dose of PCP.

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Year:  1980        PMID: 6106663     DOI: 10.1007/bf01250663

Source DB:  PubMed          Journal:  J Neural Transm            Impact factor:   3.575


  14 in total

1.  Study of a new schizophrenomimetic drug; sernyl.

Authors:  E D LUBY; B D COHEN; G ROSENBAUM; J S GOTTLIEB; R KELLEY
Journal:  AMA Arch Neurol Psychiatry       Date:  1959-03

2.  Amphetamine-induced inhibition of tyrosine hydroxylation in homogenates of rat corpus striatum.

Authors:  J E Harris; R J Baldessarini
Journal:  Neuropharmacology       Date:  1975-07       Impact factor: 5.250

3.  Characteristics of enzymic decarboxylation of L-threo-3,4-dihydroxyphenylserine using hog renal L-aromatic amino acid decarboxylase.

Authors:  C Inagaki; C Tanaka
Journal:  Biochem Pharmacol       Date:  1978-04-01       Impact factor: 5.858

Review 4.  Self-inhibition by dopaminergic neurons.

Authors:  P M Groves; C J Wilson; S J Young; G V Rebec
Journal:  Science       Date:  1975-11-07       Impact factor: 47.728

Review 5.  On stereotypy and catalepsy: studies on the effect of amphetamines and neuroleptics in rats.

Authors:  R Fog
Journal:  Acta Neurol Scand Suppl       Date:  1972

6.  Assay of tyrosine hydroxylase by coupled decarboxylation of DOPA formed from 1- 14 C-L-tyrosine.

Authors:  J C Waymire; R Bjur; N Weiner
Journal:  Anal Biochem       Date:  1971-10       Impact factor: 3.365

7.  d-Amphetamine-induced inhibition of central dopaminergic neurons: mediation by a striato-nigral feedback pathway.

Authors:  B S Bunney; G K Achajanian
Journal:  Science       Date:  1976-04-23       Impact factor: 47.728

8.  Phencyclidine-induced stereotyped behavior in monkeys: antagonism by pimozide.

Authors:  R F Schlemmer; J A Jackson; K L Preston; J P Bederka; D L Garver; J M Davis
Journal:  Eur J Pharmacol       Date:  1978-12-01       Impact factor: 4.432

9.  Dopaminergic effects of phencyclidine in rats with nigrostriatal lesions.

Authors:  M Kanner; K Finnegan; H Y Meltzer
Journal:  Psychopharmacol Commun       Date:  1975

10.  The effects of acute and chronic phencyclidine on schedule-controlled behavior in the squirrel monkey.

Authors:  L D Chait; R L Balster
Journal:  J Pharmacol Exp Ther       Date:  1978-01       Impact factor: 4.030

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  3 in total

1.  Phencyclidine treatment in mice: effects on phencyclidine binding sites and glutamate uptake in cerebral cortex preparations.

Authors:  P Saransaari; S M Lillrank; S S Oja
Journal:  J Neural Transm Gen Sect       Date:  1993

Review 2.  Tyrosine hydroxylase regulation in the central nervous system.

Authors:  J M Masserano; N Weiner
Journal:  Mol Cell Biochem       Date:  1983       Impact factor: 3.396

3.  Acute and chronic phencyclidine administration effects on the conversion of 3H-tryptophan to 3H-serotonin in rat forebrain.

Authors:  K M Johnson
Journal:  J Neural Transm       Date:  1982       Impact factor: 3.575

  3 in total

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