| Literature DB >> 6106506 |
S Abraham, L A Hillyard, F N Hansen, C Y Lin.
Abstract
Estrogen treatment decreased fatty acid synthetase and acetyl-CoA carboxylase (EC 6.4.1.2) activities and lowered the lipogenic capacity of mammary gland and the hormone-responsive, transplantable mammary adenocarcinoma R3230AC in male and female Fischer rats whereas the activity of these enzymes and the lipogenic capacity were increased in liver. Estrogen increased the activity of thioesterase II, an enzyme which terminates fatty acid synthesis at medium chain lengths, in both normal and neoplastic mammary tissue.Entities:
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Year: 1980 PMID： 6106506 DOI： 10.1016/0005-2760(80)90196-4
Source DB: PubMed Journal: Biochim Biophys Acta ISSN： 0006-3002