Literature DB >> 6106254

Clinical use of the radioreceptor assay for neuroleptics.

B M Cohen, J F Lipinski, P Q Harris, H G Pope, M Friedman.   

Abstract

The potential clinical utility of the radioreceptor assay for neuroleptics (NRRA) was examined. The NRRA was able to detect neuroleptic activity in blood specimens from patients receiving a variety of neuroleptic medications. For each medication, mean plasma neuroleptic activity was lower in patients showing a poor response to treatment than in those showing a good response. Because the range of plasma neuroleptic activities found was quite different from drug to drug, it appears that results obtained by the NRRA must be standarized for each drug.

Entities:  

Mesh:

Substances:

Year:  1980        PMID: 6106254     DOI: 10.1016/0165-1781(80)90074-8

Source DB:  PubMed          Journal:  Psychiatry Res        ISSN: 0165-1781            Impact factor:   3.222


  6 in total

1.  Neuroleptic blood levels and therapeutic effect.

Authors:  B M Cohen; J F Lipinski; H G Pope; P Q Harris; R I Altesman
Journal:  Psychopharmacology (Berl)       Date:  1980       Impact factor: 4.530

2.  Serum levels and clinical response in long-term pharmacotherapy with zuclopenthixol decanoate.

Authors:  B Szukalski; B Lipska; L Welbel; K Nurowska
Journal:  Psychopharmacology (Berl)       Date:  1986       Impact factor: 4.530

Review 3.  Plasma level monitoring of antipsychotic drugs. Clinical utility.

Authors:  S G Dahl
Journal:  Clin Pharmacokinet       Date:  1986 Jan-Feb       Impact factor: 6.447

4.  In vivo effects of psychotropic agents on the physical properties of cell membranes in the rat brain.

Authors:  B M Cohen; G S Zubenko
Journal:  Psychopharmacology (Berl)       Date:  1985       Impact factor: 4.530

5.  Dopamine, serotonin and alpha-adrenergic receptor blocking activities in serum and their relationships to prolactin level in schizophrenic patients receiving long-term chlorpromazine treatment.

Authors:  T Nakahara; M Hirano; H Uchimura; M Saito; J S Kim; T Matsumoto; H Yokoo; M Shimomura; A Mukai
Journal:  Psychopharmacology (Berl)       Date:  1983       Impact factor: 4.530

6.  Detachment of surface membrane invagination systems by cationic amphiphilic drugs.

Authors:  Sangar Osman; Kirk A Taylor; Natalie Allcock; Richard D Rainbow; Martyn P Mahaut-Smith
Journal:  Sci Rep       Date:  2016-01-04       Impact factor: 4.379

  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.