| Literature DB >> 6106099 |
J E Addiego, A J Ammann, G Schiffman, R Baehner, G Higgins, D Hammond.
Abstract
Patients with Hodgkin's disease (HD) have a high risk of overwhelming pneumococcal infections after splenectomy. Previous studies have shown that HD patients given polyvalent pneumococcal polysaccharide (PPS) vaccine after immunosuppressive therapy have a suboptimum antibody response. This study shows significant antibody response in HD patients to PPS vaccine given before radiation and chemotherapy. The same response was obtained whether the vaccine was given before or after splenectomy.Entities:
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Year: 1980 PMID: 6106099 DOI: 10.1016/s0140-6736(80)91887-5
Source DB: PubMed Journal: Lancet ISSN: 0140-6736 Impact factor: 79.321