Literature DB >> 6105395

Cerebrospinal-fluid lymphocyte populations and immune complexes in active multiple sclerosis.

P K Coyle, B R Brooks, R L Hirsch, S R Cohen, P O'Donnell, R T Johnson, J S Wolinsky.   

Abstract

A specific subpopulation of mononuclear cells bearing a surface receptor for the Fc portion of IgG was considerably reduced in the cerebrospinal fluid (CSF) of multiple sclerosis (MS) patients during exacerbation, but returned toward normal levels as the patient entered remission. Low concentrations of immune complexes were found in the CSF in nearly 50% of MS patients during exacerbations but immune complexes were not found in patients with stable MS.

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Year:  1980        PMID: 6105395     DOI: 10.1016/s0140-6736(80)90121-x

Source DB:  PubMed          Journal:  Lancet        ISSN: 0140-6736            Impact factor:   79.321


  8 in total

1.  Multiple sclerosis: II. Effects of prothymosin alpha on the autologous and allogeneic MLR in patients with multiple sclerosis.

Authors:  G J Reclos; C N Baxevanis; C Sfagos; C Papageorgiou; G C Tsokos; M Papamichail
Journal:  Clin Exp Immunol       Date:  1987-11       Impact factor: 4.330

2.  Defective autologous mixed lymphocyte reactivity in multiple sclerosis.

Authors:  R L Hirsch
Journal:  Clin Exp Immunol       Date:  1986-04       Impact factor: 4.330

3.  Immune complexes in CSF and serum in various neurological diseases.

Authors:  M Cavalli; E Merelli; P Sola; G Pirrò; P Faglioni
Journal:  Ital J Neurol Sci       Date:  1986-04

4.  Differences in interaction between immune complexes and complement receptors in serum and cerebrospinal fluid.

Authors:  M E Medof; J P Antel; J J Oger; G M Prince; B G Arnason
Journal:  Clin Exp Immunol       Date:  1982-04       Impact factor: 4.330

5.  Lymphocyte subpopulations in patients with multiple sclerosis.

Authors:  A Compston
Journal:  J Neurol Neurosurg Psychiatry       Date:  1983-02       Impact factor: 10.154

6.  Multiple sclerosis: I. Monocyte stimulatory defect in mixed lymphocyte reaction associated with clinical disease activity.

Authors:  C N Baxevanis; G J Reclos; C Sfagos; E Doufexis; C Papageorgiou; M Papamichail
Journal:  Clin Exp Immunol       Date:  1987-02       Impact factor: 4.330

7.  Intrathecal antibody synthesis to virus antigens in multiple sclerosis.

Authors:  A Salmi; M Reunanen; J Ilonen; M Panelius
Journal:  Clin Exp Immunol       Date:  1983-05       Impact factor: 4.330

Review 8.  The pathogenesis of multiple sclerosis. Additional considerations.

Authors:  C M Poser
Journal:  J Neurol Sci       Date:  1993-04       Impact factor: 3.181

  8 in total

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