Literature DB >> 6104845

Changes in opiate activity of rat pituitary following acute administration of neuroleptics.

C Spadaro, G M Scoto, P Ferri, S Ferri.   

Abstract

An increase was found in the opiate activity of pituitary extracts obtained rom rats injected with the neuroleptic drugs trifluoperazine and sulpiride. The increase of opiate activity, measured by bioassay, was particularly evident 2 h after the administration of sulpiride. Dexamethasone completely prevented the neuroleptic-induced effect. Trifluoperazine and sulpiride may have affected dopaminergic mechanisms regulating endorphin storage in the pituitary.

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Year:  1980        PMID: 6104845     DOI: 10.1007/bf00426522

Source DB:  PubMed          Journal:  Psychopharmacology (Berl)        ISSN: 0033-3158            Impact factor:   4.530


  10 in total

1.  A peptide-like substance from pituitary that acts like morphine. I. Isolation.

Authors:  H Teschemacher; K E Opheim; B M Cox; A Goldstein
Journal:  Life Sci       Date:  1975-06-15       Impact factor: 5.037

2.  The C-fragment of beta-lipotropin: an endogenous neuroleptic or antipsychotogen?

Authors:  Y F Jacquet; N Marks
Journal:  Science       Date:  1976-11-05       Impact factor: 47.728

3.  Rat striatal methionine-enkephalin content after chronic treatment with cataleptogenic and noncataleptogenic antischizophrenic drugs.

Authors:  J S Hong; H Y Yang; W Fratta; E Costa
Journal:  J Pharmacol Exp Ther       Date:  1978-04       Impact factor: 4.030

4.  MSH activity in plasma and pituitaries of rats after various treatments.

Authors:  A J Kastin; A V Schally; S Viosca; M C Miller
Journal:  Endocrinology       Date:  1969-01       Impact factor: 4.736

5.  Some relationships between endorphins and pituitary hormones.

Authors:  A Santagostino; D Cocchi; G Giagnoni; E Gori; E Muller; S Ferri
Journal:  Adv Biochem Psychopharmacol       Date:  1978

Review 6.  beta-endorphin: cellular localization, electrophysiological and behavioral effects.

Authors:  F E Bloom; J Rossier; E L Battenberg; A Bayon; E French; S J Henriksen; G R Siggins; D Segal; R Browne; N Ling; R Guillemin
Journal:  Adv Biochem Psychopharmacol       Date:  1978

7.  Antagonism of the hyperactivity induced by dopamine applied intracerebrally to the nucleus accumbens septi by typical neuroleptics and by clozapine, sulpiride and thioridazine.

Authors:  B Costall; R J Naylor
Journal:  Eur J Pharmacol       Date:  1976-01       Impact factor: 4.432

8.  beta-Endorphin: endogenous opiate or neuroleptic?

Authors:  D S Segal; R G Browne; F Bloom; N Ling; R Guillemin
Journal:  Science       Date:  1977-10-28       Impact factor: 47.728

9.  Increased CSF levels of endorphines in chronic psychosis.

Authors:  L Terenius; A Wahlström; L Lindström; E Widerlöv
Journal:  Neurosci Lett       Date:  1976-10       Impact factor: 3.046

10.  Release of beta-endorphin from rat pituitary in vitro.

Authors:  R Przewłocki; V Höllt; A Herz
Journal:  Eur J Pharmacol       Date:  1978-09-15       Impact factor: 4.432

  10 in total

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