Literature DB >> 6104733

8-Chloro-1-methyl-6-phenyl-4H-s-triazolo[4,3-a][1,4]benzodiazepines with substituents at C-4.

J B Hester, A D Rudzik, P F Von Voigtlander.   

Abstract

A series of 8-chloro-1-methyl-6-phenyl-4H-s-triazolo[4,3-a][1,4]benzodiazepines with substituents at C-4 was prepared and evaluated for antianxiety potential. It was found that substitution at this position generally decreased the activity in this series.

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Year:  1980        PMID: 6104733     DOI: 10.1021/jm00180a012

Source DB:  PubMed          Journal:  J Med Chem        ISSN: 0022-2623            Impact factor:   7.446


  1 in total

1.  1,4-Benzodiazepine N-nitrosoamidines: useful intermediates in the synthesis of tricyclic benzodiazepines.

Authors:  Santos Fustero; Javier González; Carlos del Pozo
Journal:  Molecules       Date:  2006-08-09       Impact factor: 4.411

  1 in total

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