Literature DB >> 6104515

Association of guanylate cyclase with the axoneme of retinal rods.

D Fleischman, M Denisevich, D Raveed, R G Pannbacker.   

Abstract

Axonemes were isolated from purified bovine retinal rod outer segments by dissolving the outer segment membranes in detergent and separating the axonemes by centrifugation on a linear detergent-containing sucrose density gradient. Guanylate cyclase (GTP pyrophosphate-lyase (cyclizing), EC 4.61.2) activity was concentrated in the axoneme fraction. Guanylate cyclase eluted in the void volume when detergent-solubilized rod outer segments were subjected to exclusion chromatography on Sepharose 4B. Attempts to extract guanylate cyclase from isolated axonemes with salt, EDTA, base and other reagents were successful.

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Year:  1980        PMID: 6104515     DOI: 10.1016/0304-4165(80)90419-5

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN: 0006-3002


  11 in total

1.  Excised patches of plasma membrane from vertebrate rod outer segments retain a functional phototransduction enzymatic cascade.

Authors:  E A Ertel
Journal:  Proc Natl Acad Sci U S A       Date:  1990-06       Impact factor: 11.205

2.  Plasma membrane guanylate cyclase is a multimodule transduction system.

Authors:  R K Sharma; T Duda; A Sitaramayya
Journal:  Amino Acids       Date:  1994-06       Impact factor: 3.520

3.  Cytochemical localization of guanylate cyclase in photoreceptor cells of the mouse.

Authors:  U Schraermeyer; P Esser; S Grisanti; M Rack; K Heimann
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  1997-03       Impact factor: 3.117

4.  Targeting of mouse guanylate cyclase 1 (Gucy2e) to Xenopus laevis rod outer segments.

Authors:  Sukanya Karan; Beatrice M Tam; Orson L Moritz; Wolfgang Baehr
Journal:  Vision Res       Date:  2011-09-12       Impact factor: 1.886

5.  Intestinal receptor for heat-stable enterotoxin of Escherichia coli is tightly coupled to a novel form of particulate guanylate cyclase.

Authors:  S A Waldman; T Kuno; Y Kamisaki; L Y Chang; J Gariepy; P O'Hanley; G Schoolnik; F Murad
Journal:  Infect Immun       Date:  1986-01       Impact factor: 3.441

Review 6.  Factors that affect regulation of cGMP synthesis in vertebrate photoreceptors and their genetic link to human retinal degeneration.

Authors:  Elena V Olshevskaya; Alexandre N Ermilov; Alexander M Dizhoor
Journal:  Mol Cell Biochem       Date:  2002-01       Impact factor: 3.396

7.  The proteome of the mouse photoreceptor sensory cilium complex.

Authors:  Qin Liu; Glenn Tan; Natasha Levenkova; Tiansen Li; Edward N Pugh; John J Rux; David W Speicher; Eric A Pierce
Journal:  Mol Cell Proteomics       Date:  2007-05-09       Impact factor: 5.911

8.  Interaction of retinal guanylate cyclase with the alpha subunit of transducin: potential role in transducin localization.

Authors:  Derek H Rosenzweig; K Saidas Nair; Konstantin Levay; Igor V Peshenko; John W Crabb; Alexander M Dizhoor; Vladlen Z Slepak
Journal:  Biochem J       Date:  2009-02-01       Impact factor: 3.857

9.  Light-induced changes in GTP and ATP in frog rod photoreceptors. Comparison with recovery of dark current and light sensitivity during dark adaptation.

Authors:  M S Biernbaum; M D Bownds
Journal:  J Gen Physiol       Date:  1985-01       Impact factor: 4.086

10.  In situ cGMP phosphodiesterase and photoreceptor potential in gecko retina.

Authors:  S Kawamura; M Murakami
Journal:  J Gen Physiol       Date:  1986-05       Impact factor: 4.086

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