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Literature DB >> 6103093

Angiogenic factor from synovial fluid resembling that from tumours.

R A Brown, J B Weiss, I W Tomlinson, P Phillips, S Kumar.

Abstract

Synovial fluids from 2 of 2 patients with osteoarthritis, 2 of 8 with rheumatoid arthritis, and 2 of 2 with ankylosing spondylitis contained a low-molecular-weight angiogenesis factor apparently identical with that derived from tumours. The amount of factor present was highest in patients with osteoarthritis, 2 patients with psoriatic arthropathy gave negative results. It is suggested that angiogenesis factor is involved, directly or indirectly, in the production of synovial exudate.

Entities: Disease Species

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Year: 1980 PMID： 6103093

Source DB: PubMed Journal: Lancet ISSN： 0140-6736 Impact factor: 79.321

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Cited

25 in total

1. A modified chorioallantoic membrane (CAM) assay for qualitative and quantitative study of growth factors. Studies on the effects of carriers, PBS, angiogenin, and bFGF.

Authors: J Wilting; B Christ; M Bokeloh
Journal: Anat Embryol (Berl) Date: 1991

Review 2. Hypoxia and inflammatory synovitis: observations and speculation.

Authors: C R Stevens; R B Williams; A J Farrell; D R Blake
Journal: Ann Rheum Dis Date: 1991-02 Impact factor: 19.103

3. Effect of oxygen tension on the quantities of procollagenase-activating angiogenic factor present in the developing kitten retina.

Authors: C M Taylor; J B Weiss; R D Kissun; A Garner
Journal: Br J Ophthalmol Date: 1986-03 Impact factor: 4.638

4. Morphometric analysis of blood vessels in synovial membranes obtained from clinically affected and unaffected knee joints of patients with rheumatoid arthritis.

Authors: O FitzGerald; M Soden; G Yanni; R Robinson; B Bresnihan
Journal: Ann Rheum Dis Date: 1991-11 Impact factor: 19.103

Angiogenic factor from synovial fluid resembling that from tumours.

1. A modified chorioallantoic membrane (CAM) assay for qualitative and quantitative study of growth factors. Studies on the effects of carriers, PBS, angiogenin, and bFGF.

Review 2. Hypoxia and inflammatory synovitis: observations and speculation.

3. Effect of oxygen tension on the quantities of procollagenase-activating angiogenic factor present in the developing kitten retina.

4. Morphometric analysis of blood vessels in synovial membranes obtained from clinically affected and unaffected knee joints of patients with rheumatoid arthritis.

Review 5. The vasculature in rheumatoid arthritis: cause or consequence?

6. Angiogenesis in rheumatoid arthritis: implications for future therapeutic strategies.

7. Thiol-containing compounds inhibit the production of monocyte/macrophage-derived angiogenic activity.

Review 8. Tumor-derived angiogenesis factors from rat Walker 256 carcinoma: an experimental investigation and review.

9. Characterization and quantification of copper sulfate-induced vascularization of the rabbit cornea.

10. Interleukin-8 stimulates angiogenesis in rats.