Literature DB >> 6102627

Clavulanic acid and amoxycillin: a clinical, bacteriological, and pharmacological study.

A P Ball, A M Geddes, P G Davey, I D Farrell, G R Brookes.   

Abstract

Clavulanic acid is an inhibitor of certain beta-lactamases, notably those enzymes which inactivate the penicillins and cause resistance of important bacteria to these antibiotics. Microbiological, pharmacological, and clinical studies show that clavulanic acid in combination with amoxycillin is effective and safe in the treatment of urinary-tract infection caused by amoxycillin-resistant bacteria.

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Year:  1980        PMID： 6102627     DOI： 10.1016/s0140-6736(80)91118-6

Source DB:  PubMed          Journal:  Lancet        ISSN： 0140-6736            Impact factor:   79.321


  27 in total

1.  In vitro susceptibility of Mycobacterium tuberculosis isolates to an oral carbapenem alone or in combination with β-lactamase inhibitors.

Authors:  Yasuhiro Horita; Shinji Maeda; Yuko Kazumi; Norio Doi
Journal:  Antimicrob Agents Chemother       Date:  2014-09-15       Impact factor: 5.191

2.  Pharmacokinetic study of a paediatric formulation of amoxycillin and clavulanic acid in children.

Authors:  C H van Niekerk; J van den Ende; H K Hundt; E A Louw
Journal:  Eur J Clin Pharmacol       Date:  1985       Impact factor: 2.953

Review 3.  Beta-lactamase inhibitors from laboratory to clinic.

Authors:  K Bush
Journal:  Clin Microbiol Rev       Date:  1988-01       Impact factor: 26.132

4.  Susceptibility of gram-negative bacteria and Staphylococcus aureus to combinations of ticarcillin and clavulanic acid.

Authors:  P Casey; M Glauser
Journal:  Eur J Clin Microbiol       Date:  1983-12       Impact factor: 3.267

5.  Activities of amoxicillin and clavulanic acid combinations against urinary tract infections.

Authors:  F Crokaert; M P van der Linden; E Yourassowsky
Journal:  Antimicrob Agents Chemother       Date:  1982-08       Impact factor: 5.191

6.  Amoxicillin-clavulanate (Clavulin). Infectious Diseases and Immunization Committee, Canadian Paediatric Society.

Authors: 
Journal:  CMAJ       Date:  1985-10-15       Impact factor: 8.262

7.  Amoxicillin-clavulanic acid versus cefaclor in the treatment of urinary tract infections and their effects on the urogenital and rectal flora.

Authors:  A Iravani; G A Richard
Journal:  Antimicrob Agents Chemother       Date:  1986-01       Impact factor: 5.191

8.  In vitro and in vivo synergism between amoxicillin and clavulanic acid against ampicillin-resistant Haemophilus influenzae type b.

Authors:  R Yogev; C Melick; W J Kabat
Journal:  Antimicrob Agents Chemother       Date:  1981-06       Impact factor: 5.191

9.  Amoxycillin and clavulanic acid in the treatment of urinary infection.

Authors:  L G Al Roomi; A M Sutton; F Cockburn; T A McAllister
Journal:  Arch Dis Child       Date:  1984-03       Impact factor: 3.791

10.  Amoxicillin combined with clavulanic acid for the treatment of soft tissue infections in children.

Authors:  G R Fleisher; C M Wilmott; J M Campos
Journal:  Antimicrob Agents Chemother       Date:  1983-11       Impact factor: 5.191
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