Literature DB >> 6102129

In vivo assessment of extrahepatic conjugative metabolism in first pass effects using the model compound phenol.

M K Cassidy, J B Houston.   

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Year:  1980        PMID: 6102129     DOI: 10.1111/j.2042-7158.1980.tb12846.x

Source DB:  PubMed          Journal:  J Pharm Pharmacol        ISSN: 0022-3573            Impact factor:   3.765


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  17 in total

1.  Relationship of apparent systemic clearance to individual organ clearances: effect of pulmonary clearance and site of drug administration and measurement.

Authors:  R Mehvar
Journal:  Pharm Res       Date:  1991-03       Impact factor: 4.200

2.  Sites of first-pass bioactivation (hydrolysis) of orally administered zofenopril calcium in dogs.

Authors:  R A Morrison; D E Burkett; M E Arnold; C J D'Arienzo; S H Weinstein
Journal:  Pharm Res       Date:  1991-03       Impact factor: 4.200

3.  Prediction of diazepam disposition in the rat and man by a physiologically based pharmacokinetic model.

Authors:  Y Igari; Y Sugiyama; Y Sawada; T Iga; M Hanano
Journal:  J Pharmacokinet Biopharm       Date:  1983-12

4.  Mephenytoin stereoselective elimination in the rat: II. Comparison of mephenytoin stereoselective clearance during chronic intravenous and hepatic portal vein administration.

Authors:  S H Akrawi; P J Wedlund
Journal:  Eur J Drug Metab Pharmacokinet       Date:  1989 Oct-Dec       Impact factor: 2.441

5.  Pulmonary first-pass and steady-state metabolism of phenols.

Authors:  P A Dickinson; G Taylor
Journal:  Pharm Res       Date:  1996-05       Impact factor: 4.200

6.  First-pass effect of cis-3,4-dichloro-N-methyl-N-(2-(1-pyrrolidinyl)- cyclohexyl)-benzamide (U-54494) in rats--a model with multiple cannulas for investigation of gastrointestinal and hepatic metabolism.

Authors:  W Z Zhong; M G Williams; K J Cook; T L VandeGiessen; B W Jones; K E Rousch
Journal:  Pharm Res       Date:  1994-11       Impact factor: 4.200

7.  Time-dependent variations in the organ extraction ratios of acetaminophen in rat.

Authors:  P M Bélanger; M Lalande; F Doré; G Labrecque
Journal:  J Pharmacokinet Biopharm       Date:  1987-04

8.  Evaluating barriers to bioavailability in vivo: validation of a technique for separately assessing gastrointestinal absorption and hepatic extraction.

Authors:  Laura Letendre; Mark Scott; Glenn Dobson; Ismael Hidalgo; Bruce Aungst
Journal:  Pharm Res       Date:  2004-08       Impact factor: 4.200

9.  Pulmonary metabolism of resveratrol: in vitro and in vivo evidence.

Authors:  Satish Sharan; Swati Nagar
Journal:  Drug Metab Dispos       Date:  2013-03-08       Impact factor: 3.922

10.  Extrahepatic metabolism of frusemide in anaesthetized rabbits.

Authors:  J Vergés; L Héroux; H Maurice; P du Souich
Journal:  Br J Pharmacol       Date:  1995-11       Impact factor: 8.739

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