Literature DB >> 6101511

gamma-Glutamyl transpeptidase in isolated brain endothelial cells: induction by glial cells in vitro.

L E DeBault, P A Cancilla.   

Abstract

The endothelia of microvessels isolated from mouse brain by mechanical means are rich in gamma-glutamyl transpeptidase; however, the enzyme often disappears when the cells migrate or proliferate from the microvessel isolates. In an endothelial cell line derived from similar isolates and negative for gamma-glutamyl transpeptidase, the enzyme could be induced in the endothelial cells when they were cocultured with glial cells. Thus there may be a requirement for continuous induction of gamma-glutamyl transpeptidase in brain microvessels by adjacent glial cells.

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Year:  1980        PMID： 6101511     DOI： 10.1126/science.6101511

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  71 in total

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Journal:  Cell Mol Neurobiol       Date:  2000-02       Impact factor: 5.046

Review 2.  Drug transport across the blood--brain barrier. I. Anatomical and physiological aspects.

Authors:  J B Van Bree; A G De Boer; M Danhof; D D Breimer
Journal:  Pharm Weekbl Sci       Date:  1992-10-16

3.  An in vitro model for cell-cell interactions.

Authors:  K B Saunders; P A D'Amore
Journal:  In Vitro Cell Dev Biol       Date:  1992 Jul-Aug

Review 4.  In vitro models of the blood-brain barrier: An overview of commonly used brain endothelial cell culture models and guidelines for their use.

Authors:  Hans C Helms; N Joan Abbott; Malgorzata Burek; Romeo Cecchelli; Pierre-Olivier Couraud; Maria A Deli; Carola Förster; Hans J Galla; Ignacio A Romero; Eric V Shusta; Matthew J Stebbins; Elodie Vandenhaute; Babette Weksler; Birger Brodin
Journal:  J Cereb Blood Flow Metab       Date:  2016-02-11       Impact factor: 6.200

Review 5.  In search of the astrocytic factor(s) modulating blood-brain barrier functions in brain capillary endothelial cells in vitro.

Authors:  R F Haseloff; I E Blasig; H C Bauer; H Bauer
Journal:  Cell Mol Neurobiol       Date:  2005-02       Impact factor: 5.046

Review 6.  Permeability studies on in vitro blood-brain barrier models: physiology, pathology, and pharmacology.

Authors:  Máiria A Deli; Csongor S Abrahám; Yasufumi Kataoka; Masami Niwa
Journal:  Cell Mol Neurobiol       Date:  2005-02       Impact factor: 5.046

7.  Morphological differentiation of endothelial cells co-cultured with astrocytes on type-I or type-IV collagen.

Authors:  M Tagami; K Yamagata; H Fujino; A Kubota; Y Nara; Y Yamori
Journal:  Cell Tissue Res       Date:  1992-05       Impact factor: 5.249

8.  Products of cultured neuroglial cells: II. The production of fibronectin by C6 glioma cells.

Authors:  J R Baldwin; P E McKeever; T R Booker
Journal:  Neurochem Res       Date:  1985-05       Impact factor: 3.996

9.  Interleukin 1 beta up-regulates the expression of sulfoglucuronosyl paragloboside, a ligand for L-selectin, in brain microvascular endothelial cells.

Authors:  T Kanda; M Yamawaki; T Ariga; R K Yu
Journal:  Proc Natl Acad Sci U S A       Date:  1995-08-15       Impact factor: 11.205

10.  Effect of hydrocortisone and nicotinamide on gamma glutamyltransferase in primary cultures of rat hepatocytes.

Authors:  M R Rosenberg; S C Strom; G Michalopoulos
Journal:  In Vitro       Date:  1982-09
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