Transglutaminase activity of cultured human prostatic epithelium.

A transglutaminase was extracted from cultured human prostatic adenocarcinoma cells. The enzyme did not exist as a zymogen and had an apparent molecular weight of 72,000 +/- 4,000 by gel filtration. Although the role of this transglutaminase in the human prostate is uncertain, it may be a useful marker for prostatic cells in vitro.