Literature DB >> 6101309

Histochemical demonstration of enhanced glutathione content in enzyme-altered islands induced by carcinogens in rat liver.

E Deml, D Oesterle.   

Abstract

The presence of glutathione was demonstrated histochemically in livers of rats treated with diethylnitrosamine or N-nitrosomorpholine. Glutathione content was markedly elevated in adenosine triphosphatase-deficient, gamma-glutamyltranspeptidase-positive hyperplastic cell islands. This finding may partly explain the increased resistance of hyperplastic cells to cytotoxic actions of hepatocarcinogens.

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Year:  1980        PMID： 6101309

Source DB:  PubMed          Journal:  Cancer Res        ISSN： 0008-5472            Impact factor:   12.701


  10 in total

1.  Glutathione replenishment capacity is lower in isolated perivenous than in periportal hepatocytes.

Authors:  Y Kera; K E Penttilä; K O Lindros
Journal:  Biochem J       Date:  1988-09-01       Impact factor: 3.857

Review 2.  Tumor promotion in the liver.

Authors:  R Schulte-Hermann
Journal:  Arch Toxicol       Date:  1985-08       Impact factor: 5.153

3.  Comparison of killing of gram-negative and gram-positive bacteria by pure singlet oxygen.

Authors:  T A Dahl; W R Midden; P E Hartman
Journal:  J Bacteriol       Date:  1989-04       Impact factor: 3.490

Review 4.  gamma-Glutamyltranspeptidase: a tumour cell marker with a pharmacological function.

Authors:  M Vanderlaan; W Phares
Journal:  Histochem J       Date:  1981-09

5.  Amplification and increased expression of alpha class glutathione S-transferase-encoding genes associated with resistance to nitrogen mustards.

Authors:  A D Lewis; I D Hickson; C N Robson; A L Harris; J D Hayes; S A Griffiths; M M Manson; A E Hall; J E Moss; C R Wolf
Journal:  Proc Natl Acad Sci U S A       Date:  1988-11       Impact factor: 11.205

Review 6.  Enzymes of glutathione metabolism as biochemical markers during hepatocarcinogenesis.

Authors:  S Hendrich; H C Pitot
Journal:  Cancer Metastasis Rev       Date:  1987       Impact factor: 9.264

7.  Glutathione and gamma-glutamyl transpeptidase are differentially distributed in the olfactory mucosa of rats.

Authors:  N S Krishna; M L Getchell; S S Tate; F L Margolis; T V Getchell
Journal:  Cell Tissue Res       Date:  1992-12       Impact factor: 5.249

8.  Distinctive biochemical pattern associated with resistance of hepatocytes in hepatocyte nodules during liver carcinogenesis.

Authors:  L Eriksson; M Ahluwalia; J Spiewak; G Lee; D S Sarma; M J Roomi; E Farber
Journal:  Environ Health Perspect       Date:  1983-03       Impact factor: 9.031

9.  Glutathione localisation in benign and malignant human breast lesions.

Authors:  G I Murray; M D Burke; S W Ewen
Journal:  Br J Cancer       Date:  1987-06       Impact factor: 7.640

Review 10.  New Insights into the Role of Glutathione in the Mechanism of Fever.

Authors:  Sylwia Wrotek; Justyna Sobocińska; Henryk M Kozłowski; Małgorzata Pawlikowska; Tomasz Jędrzejewski; Artur Dzialuk
Journal:  Int J Mol Sci       Date:  2020-02-19       Impact factor: 5.923
  10 in total

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