Literature DB >> 6099512

ACTH, cortisol and beta-endorphin response to metyrapone testing during chronic methadone maintenance treatment in humans.

M J Kreek, J Ragunath, S Plevy, D Hamer, B Schneider, N Hartman.   

Abstract

Normal responses to metyrapone were observed in most steady-state methadone maintained treatment patients. These preliminary studies suggest that in recently detoxified methadone maintained treatment patients, there may be an exaggerated response of the hypothalamic-pituitary-adrenal axis to metyrapone.

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Year:  1984        PMID： 6099512     DOI： 10.1016/0143-4179(84)90081-7

Source DB:  PubMed          Journal:  Neuropeptides        ISSN： 0143-4179            Impact factor:   3.286


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