Literature DB >> 6098460

Tracts of high or low sequence divergence in the mouse major histocompatibility complex.

M Steinmetz, M Malissen, L Hood, A Orn, R A Maki, G R Dastoornikoo, D Stephan, E Gibb, R Romaniuk.   

Abstract

The K, I and S regions of the mouse major histocompatibility complex (MHC) are composed of long tracts of DNA which differ in sequence divergence. A correlation exists between the location of an MHC gene in a variable or conserved chromosomal tract and the degree of polymorphism and diversity of the proteins encoded by its alleles. Variable tracts appear to be the result of mechanisms which mutate certain coding and non-coding sequences to the same extent and selective pressures operating on the genes.

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Year:  1984        PMID： 6098460      PMCID： PMC557803          DOI： 10.1002/j.1460-2075.1984.tb02246.x

Source DB:  PubMed          Journal:  EMBO J        ISSN： 0261-4189            Impact factor:   11.598


  56 in total

1.  Clusters of genes encoding mouse transplantation antigens.

Authors:  M Steinmetz; A Winoto; K Minard; L Hood
Journal:  Cell       Date:  1982-03       Impact factor: 41.582

2.  Cell-type-specific cDNA probes and the murine I region: the localization and orientation of Ad alpha.

Authors:  M M Davis; D I Cohen; E A Nielsen; M Steinmetz; W E Paul; L Hood
Journal:  Proc Natl Acad Sci U S A       Date:  1984-04       Impact factor: 11.205

3.  Expression of hemolytically active murine fourth component of complement in transfected L cells.

Authors:  D D Chaplin; R Sackstein; D H Perlmutter; J H Weis; T A Kruse; J Coligan; H R Colten; J G Seidman
Journal:  Cell       Date:  1984-06       Impact factor: 41.582

4.  Six HLA-D region alpha-chain genes on human chromosome 6: polymorphisms and associations of DC alpha-related sequences with DR types.

Authors:  R S Spielman; J Lee; W F Bodmer; J G Bodmer; J Trowsdale
Journal:  Proc Natl Acad Sci U S A       Date:  1984-06       Impact factor: 11.205

5.  The T cell receptor beta chain genes are located on chromosome 6 in mice and chromosome 7 in humans.

Authors:  N Caccia; M Kronenberg; D Saxe; R Haars; G A Bruns; J Goverman; M Malissen; H Willard; Y Yoshikai; M Simon
Journal:  Cell       Date:  1984-07       Impact factor: 41.582

6.  Organization of the constant-region gene family of the mouse immunoglobulin heavy chain.

Authors:  A Shimizu; N Takahashi; Y Yaoita; T Honjo
Journal:  Cell       Date:  1982-03       Impact factor: 41.582

7.  Isolation of transforming DNA by cosmid rescue.

Authors:  T Lund; F G Grosveld; R A Flavell
Journal:  Proc Natl Acad Sci U S A       Date:  1982-01       Impact factor: 11.205

8.  Eo: a history of a mutation.

Authors:  Z Dembić; P A Singer; J Klein
Journal:  EMBO J       Date:  1984-07       Impact factor: 11.598

9.  Structure of the murine Ia-associated invariant (Ii) chain as deduced from a cDNA clone.

Authors:  P A Singer; W Lauer; Z Dembić; W E Mayer; J Lipp; N Koch; G Hämmerling; J Klein; B Dobberstein
Journal:  EMBO J       Date:  1984-04       Impact factor: 11.598

10.  The nucleotide sequence of the murine I-E beta b immune response gene: evidence for gene conversion events in class II genes of the major histocompatibility complex.

Authors:  G Widera; R A Flavell
Journal:  EMBO J       Date:  1984-06       Impact factor: 11.598
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  41 in total

1.  PFGE mapping and RFLP analysis of the S/D region of the mouse H-2 complex.

Authors:  W P Lafuse; D Lanning; T Spies; C S David
Journal:  Immunogenetics       Date:  1992       Impact factor: 2.846

2.  Evolution of the mouse H-2K region: a hot spot of mutation associated with genes transcribed in embryos and/or germ cells.

Authors:  Y I Yeom; K Abe; K Artzt
Journal:  Genetics       Date:  1992-03       Impact factor: 4.562

3.  Molecular organization of the D-Qa region of t-haplotypes suggests that recombination is an important mechanism for generating genetic diversity of the major histocompatibility complex.

Authors:  H Uehara; K Abe; L Flaherty; D Bennett; K Artzt
Journal:  Mamm Genome       Date:  1991       Impact factor: 2.957

4.  Structural and genetic properties of the Eb recombinational hotspot in the mouse.

Authors:  E J Zimmerer; H C Passmore
Journal:  Immunogenetics       Date:  1991       Impact factor: 2.846

Review 5.  Class I genes and molecules: an update.

Authors:  A M Lew; E P Lillehoj; E P Cowan; W L Maloy; M R van Schravendijk; J E Coligan
Journal:  Immunology       Date:  1986-01       Impact factor: 7.397

6.  Restriction fragment length polymorphism analysis of factor B and C2 genes in H-2 recombinant mouse strains.

Authors:  W P Lafuse; L Castle; C S David
Journal:  Immunogenetics       Date:  1990       Impact factor: 2.846

7.  The rosy region of Drosophila melanogaster and Drosophila simulans. I. Contrasting levels of naturally occurring DNA restriction map variation and divergence.

Authors:  C F Aquadro; K M Lado; W A Noon
Journal:  Genetics       Date:  1988-08       Impact factor: 4.562

8.  Restriction fragment analysis of H-2 recombinant mouse strains with crossovers between E alpha and C4 genes.

Authors:  W P Lafuse; S T Lee; L Castle; C S David
Journal:  Immunogenetics       Date:  1989       Impact factor: 2.846

9.  Remarkable sequence conservation of the HLA-DQB2 locus (DX beta) within the highly polymorphic DQ subregion of the human MHC.

Authors:  J Berdoz; J M Tiercy; P Rollini; B Mach; J Gorski
Journal:  Immunogenetics       Date:  1989       Impact factor: 2.846

10.  Cotransfer of the Ed alpha and Ad beta genes into L cells results in the surface expression of a functional mixed-isotype Ia molecule.

Authors:  B Malissen; N Shastri; M Pierres; L Hood
Journal:  Proc Natl Acad Sci U S A       Date:  1986-06       Impact factor: 11.205
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