Literature DB >> 6096681

Possible mechanisms of action of nitrous oxide at the opioid receptor.

M A Gillman.   

Abstract

The difference between the analgesic and anesthetic effects of Nitrous Oxide (N2O) is emphasized. Evidence is presented indicating that N2O analgesia is mediated by an interaction with opioid receptors. Possible mechanisms by which so small a molecule as N2O could interact with the mu opioid receptor are proposed.

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Year:  1984        PMID: 6096681     DOI: 10.1016/0306-9877(84)90114-2

Source DB:  PubMed          Journal:  Med Hypotheses        ISSN: 0306-9877            Impact factor:   1.538


  3 in total

1.  Comparison of nitrous oxide, morphine and diazepam effects in the mouse staircase test.

Authors:  R M Quock; J A Wojcechowskyj; D E Emmanouil
Journal:  Psychopharmacology (Berl)       Date:  1987       Impact factor: 4.530

2.  Cardiovascular influences of nitrous oxide in spontaneously hypertensive rats.

Authors:  R J Henry; R M Quock
Journal:  Anesth Prog       Date:  1989 May-Jun

Review 3.  Neurobiology of nitrous oxide-induced antinociceptive effects.

Authors:  Masahiko Fujinaga; Mervyn Maze
Journal:  Mol Neurobiol       Date:  2002-04       Impact factor: 5.590

  3 in total

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