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Literature DB >> 6095788

BK virus specific IgM responses in cord sera, young children and healthy adults detected by RIA.

D W Brown, S D Gardner, P E Gibson, A M Field.

Abstract

An IgM capture solid-phase radioimmunoassay (MACRIA) for BK virus (BKV) specific IgM is described. This test was found to be more sensitive in detecting BKV specific IgM than both haemagglutination inhibition and immune electron microscopy with serum fractions from sucrose density gradients. The use of this specific assay allowed large numbers of sera to be examined with ease so that the distribution of BKV specific IgM in different populations could be studied more fully. BKV specific IgM was detected in 11/300 sera from London blood donors, in 24/114 sera from children aged between 2 and 11 years admitted to a paediatric unit and 14/79 sera taken from children aged between 2 and 5 years for the investigation of anti-streptolysin 0 titres. BKV specific IgM was not detected in 404 cord sera examined to investigate the transplacental transmission of BK virus.

Entities: Chemical Species

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Year: 1984 PMID： 6095788 DOI： 10.1007/bf01311159

Source DB: PubMed Journal: Arch Virol ISSN： 0304-8608 Impact factor: 2.574

24 in total

1. BK virus: II. Serologic studies in children with congenital disease and patients with malignant tumors and immunodeficiencies.

Authors: H J Rziha; B H Belohradsky; U Schneider; H U Schwenk; G W Bornkamm; H zur Hausen
Journal: Med Microbiol Immunol Date: 1978-07-04 Impact factor: 3.402

BK virus specific IgM responses in cord sera, young children and healthy adults detected by RIA.

1. BK virus: II. Serologic studies in children with congenital disease and patients with malignant tumors and immunodeficiencies.

2. BK virus: I. Seroepidemiologic studies and serologic response to viral infection.

3. New human papovavirus (B.K.) isolated from urine after renal transplantation.

4. A search for a characteristic illness in children with serological evidence of viral or toxoplasma infection.

5. Isolation of papovavirus from brain tumor and urine of a patient with Wiskott-Aldrich syndrome.

6. Reactivation of polyoma virus in kidneys of persistently infected mice during pregnancy.

7. Transplacental transmission of polyoma virus in mice.

8. Human polyomavirus infection in renal allograft recipients.

9. Rubella-specific IgM reactivity in sera from cases of infectious mononucleosis.

10. Rubella-specific IgM detected by an antibody capture assay/ELISA technique.

1. JC virus associated meningoencephalitis in an immunocompetent girl.

2. Age-specific seroprevalence of Merkel cell polyomavirus, BK virus, and JC virus.

3. Age-dependent prevalence of BK virus IgG and IgM antibodies measured by enzyme-linked immunosorbent assays (ELISA).

4. Frequent detection of polyomaviruses in stool samples from hospitalized children.

5. Viral regulatory region effects on vertical transmission of polyomavirus SV40 in hamsters.

6. Newly discovered KI, WU, and Merkel cell polyomaviruses: no evidence of mother-to-fetus transmission.

Review 7. Different behaviour of BK-virus infection in liver transplant recipients.

8. Prevalence of Merkel Cell Polyomavirus in Tehran: An Age-Specific Serological Study.

Review 9. Human polyomavirus reactivation: disease pathogenesis and treatment approaches.