Literature DB >> 6095439

Secretion of gamma-interferon at the cellular level. Induction by Epstein-Barr virus.

U Andersson, O Martinez-Maza, J Andersson, S Britton, H Gadler, M De Ley, S Modrow.   

Abstract

Using a haemolytic plaque assay for gamma-interferon (IFN-gamma) secretion we found that in vitro Epstein-Barr virus (EBV) exposure of peripheral blood mononuclear cells from EBV immune individuals led to IFN-gamma secretion, which was apparent within 6 h after virus contact and peaked 12-24 h after induction. Live, ultraviolet-light-irradiated and heat-inactivated virions all caused IFN-gamma secretion. In contrast, blood mononuclear cells from EBV non-immune adults or neonates could not be activated to IFN-gamma production by EBV.

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Year:  1984        PMID： 6095439     DOI： 10.1111/j.1365-3083.1984.tb01021.x

Source DB:  PubMed          Journal:  Scand J Immunol        ISSN： 0300-9475            Impact factor:   3.487


  7 in total

1.  Epstein-Barr virus recombinants with specifically mutated BCRF1 genes.

Authors:  S Swaminathan; R Hesselton; J Sullivan; E Kieff
Journal:  J Virol       Date:  1993-12       Impact factor: 5.103

2.  Interleukin 2 and gamma interferon production, interleukin 2 receptor expression, and DNA synthesis induced by tularemia antigen in vitro after natural infection or vaccination.

Authors:  R Karttunen; G Andersson; H P Ekre; K Juutinen; H M Surcel; H Syrjälä; E Herva
Journal:  J Clin Microbiol       Date:  1987-06       Impact factor: 5.948

3.  A single cell assay for the study of gamma-interferon formation in leprosy patients.

Authors:  J Lindh; U Anderson; S Britton; M De Ley
Journal:  Clin Exp Immunol       Date:  1987-01       Impact factor: 4.330

4.  Effects of pure interferons on Epstein-Barr virus infection in vitro.

Authors:  J P Andersson; U G Andersson; I T Ernberg; S F Britton; M DeLey
Journal:  J Virol       Date:  1985-05       Impact factor: 5.103

5.  Immune-specific gamma interferon production correlates with lymphocyte blastogenesis.

Authors:  A D D'Andrea; S A Plotkin; S D Douglas; R A Polin
Journal:  J Clin Microbiol       Date:  1986-05       Impact factor: 5.948

6.  Epstein-barr virus-induced changes in B-lymphocyte gene expression.

Authors:  Kara L Carter; Ellen Cahir-McFarland; Elliott Kieff
Journal:  J Virol       Date:  2002-10       Impact factor: 5.103

7.  Increased spontaneous immunoglobulin secretion associated with cyclophosphamide-induced immune suppression.

Authors:  O Martínez-Maza; D J Moody; A R Rezai; G W Ellison; L W Myers; W W Tourtellotte; J L Fahey
Journal:  J Clin Immunol       Date:  1987-03       Impact factor: 8.317
  7 in total

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