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Literature DB >> 6095113

Adenovirus-2 E1A products repress enhancer-induced stimulation of transcription.

Abstract

The adenovirus-2 early region 1A (E1A) products repress activation of transcription induced by the simian virus 40, polyoma virus and adenovirus-2 E1A enhancers. The repression probably involves an interaction between the enhancer elements and a trans-acting factor(s), possibly the E1A products themselves.

Entities: Disease Species

Mesh：

Substances：
DNA Restriction Enzymes

Year: 1984 PMID： 6095113 DOI： 10.1038/312608a0

Source DB: PubMed Journal: Nature ISSN： 0028-0836 Impact factor: 49.962

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Cited

228 in total

1. Polyomavirus genome and polyomavirus enhancer-driven gene expression during myogenesis.

Authors: R Maione; A Felsani; L Pozzi; M Caruso; P Amati
Journal: J Virol Date: 1989-11 Impact factor: 5.103

2. The regions important for the activator and repressor functions of herpes simplex virus type 1 alpha protein ICP27 map to the C-terminal half of the molecule.

Authors: M A Hardwicke; P J Vaughan; R E Sekulovich; R O'Conner; R M Sandri-Goldin
Journal: J Virol Date: 1989-11 Impact factor: 5.103

3. Adenovirus infection of differentiated F9 cells results in a global shut-off of differentiation-induced gene expression.

Authors: R J Weigel; J R Nevins
Journal: Nucleic Acids Res Date: 1990-10-25 Impact factor: 16.971

9. Pancreatic beta-cell-type-specific expression of the rat insulin II gene is controlled by positive and negative cellular transcriptional elements.

Authors: J Whelan; D Poon; P A Weil; R Stein
Journal: Mol Cell Biol Date: 1989-08 Impact factor: 4.272

10. Rapid mRNA degradation mediated by the c-fos 3' AU-rich element and that mediated by the granulocyte-macrophage colony-stimulating factor 3' AU-rich element occur through similar polysome-associated mechanisms.

Authors: E Winstall; M Gamache; V Raymond
Journal: Mol Cell Biol Date: 1995-07 Impact factor: 4.272

Adenovirus-2 E1A products repress enhancer-induced stimulation of transcription.

1. Polyomavirus genome and polyomavirus enhancer-driven gene expression during myogenesis.

2. The regions important for the activator and repressor functions of herpes simplex virus type 1 alpha protein ICP27 map to the C-terminal half of the molecule.

3. Adenovirus infection of differentiated F9 cells results in a global shut-off of differentiation-induced gene expression.

4. The SV40 early transcriptional regulatory element is unable to direct gene expression in pituitary GH-3 cells.

5. Promoter-specific trans-activation by the adenovirus E1A12S product involves separate E1A domains.

6. 5' untranslated sequences modulate rapid mRNA degradation mediated by 3' AU-rich element in v-/c-fos recombinants.

7. DNA-binding properties of the E1A-associated 300-kilodalton protein.

8. Upstream DNA sequences determine different autoregulatory responses of the adenovirus types 5 and 3 E1A promoters.

9. Pancreatic beta-cell-type-specific expression of the rat insulin II gene is controlled by positive and negative cellular transcriptional elements.

10. Rapid mRNA degradation mediated by the c-fos 3' AU-rich element and that mediated by the granulocyte-macrophage colony-stimulating factor 3' AU-rich element occur through similar polysome-associated mechanisms.