Literature DB >> 6095112

Recombinant antibodies possessing novel effector functions.

M S Neuberger, G T Williams, R O Fox.   

Abstract

The introduction into lymphocytes of immunoglobulin-gene DNA that has been manipulated in vitro allows the production of novel antibodies. In this way, cell lines have been established that secrete hapten-specific antibodies in which the Fc portion has been replaced either with an active enzyme moiety or with polypeptide displaying c-myc antigenic determinants.

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Year:  1984        PMID： 6095112     DOI： 10.1038/312604a0

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


  50 in total

Review 1.  Immunomodulation of autoimmune responses with monoclonal antibodies and immunoadhesins: treatment of ocular inflammatory disease in the next millennium.

Authors:  A D Dick; J D Isaacs
Journal:  Br J Ophthalmol       Date:  1999-11       Impact factor: 4.638

2.  The principle of delivery of T cell epitopes to antigen-presenting cells applied to peptides from influenza virus, ovalbumin, and hen egg lysozyme: implications for peptide vaccination.

Authors:  I B Rasmussen; E Lunde; T E Michaelsen; B Bogen; I Sandlie
Journal:  Proc Natl Acad Sci U S A       Date:  2001-08-21       Impact factor: 11.205

3.  Recombinant antibody-metallothionein: design and evaluation for radioimmunoimaging.

Authors:  C Das; P V Kulkarni; A Constantinescu; P Antich; F R Blattner; P W Tucker
Journal:  Proc Natl Acad Sci U S A       Date:  1992-10-15       Impact factor: 11.205

Review 4.  Recombinant antibodies for the diagnosis and treatment of cancer.

Authors:  Jürgen Krauss
Journal:  Mol Biotechnol       Date:  2003-09       Impact factor: 2.695

Review 5.  The second century of the antibody. Molecular perspectives in regulation, pathophysiology, and therapeutic applications.

Authors:  J Braun; A Saxon; R Wall; S L Morrison
Journal:  West J Med       Date:  1992-08

6.  'Phytoantibodies': a general vector for the expression of immunoglobulin domains in transgenic plants.

Authors:  E Benvenuto; R J Ordàs; R Tavazza; G Ancora; S Biocca; A Cattaneo; P Galeffi
Journal:  Plant Mol Biol       Date:  1991-10       Impact factor: 4.076

Review 7.  The birth pangs of monoclonal antibody therapeutics: the failure and legacy of Centoxin.

Authors:  Lara Marks
Journal:  MAbs       Date:  2012-04-26       Impact factor: 5.857

8.  Monoclonal antibodies.

Authors:  S P Cole
Journal:  Can Fam Physician       Date:  1987-02       Impact factor: 3.275

9.  Serum half-life and tumor localization of a chimeric antibody deleted of the CH2 domain and directed against the disialoganglioside GD2.

Authors:  B M Mueller; R A Reisfeld; S D Gillies
Journal:  Proc Natl Acad Sci U S A       Date:  1990-08       Impact factor: 11.205

10.  EcoK selection vectors for shotgun cloning into M13 and deletion mutagenesis.

Authors:  M M Waye; M E Verhoeyen; P T Jones; G Winter
Journal:  Nucleic Acids Res       Date:  1985-12-09       Impact factor: 16.971
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