| Literature DB >> 6094934 |
T Okajima, S Ikuyama, K Kato, H Ibayashi.
Abstract
Intravenous injection of (1-24) ACTH and 2-deoxy-d-glucose (2DG) stimulated the plasma epinephrine and norepinephrine levels in pentobarbital-anesthetized male rats. Naloxone, a specific opiate antagonist, inhibited the plasma epinephrine response to ACTH but not to 2DG. Norepinephrine release induced by ACTH or 2DG was not affected by naloxone. These results suggest that the opioid peptidergic synapse might be involved in the ACTH- but not in the 2DG-induced epinephrine release.Entities:
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Year: 1984 PMID: 6094934 DOI: 10.1016/0024-3205(84)90457-0
Source DB: PubMed Journal: Life Sci ISSN: 0024-3205 Impact factor: 5.037