Literature DB >> 6094727

Herpes simplex virus and Alzheimer's disease: a search for virus DNA by spot hybridisation.

G R Taylor, T J Crow, D A Markakis, R Lofthouse, S Neeley, G I Carter.   

Abstract

A sensitive hybridisation screening technique (spot hybridisation) was used to search post-mortem brain DNA extracts for herpes simplex I virus sequences in non-neurological controls, Alzheimer's disease cases and Herpes simplex virus infected mice. A reconstruction experiment showed that 0.1 herpes genome equivalents per cell could be detected in 100 micrograms tissue extracts. Although herpes sequences were readily detected in infected mice, none of the human brains examined could be shown to contain such sequences.

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Year:  1984        PMID： 6094727      PMCID： PMC1028034          DOI： 10.1136/jnnp.47.10.1061

Source DB:  PubMed          Journal:  J Neurol Neurosurg Psychiatry        ISSN： 0022-3050            Impact factor:   10.154


  17 in total

1.  Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I.

Authors:  P W Rigby; M Dieckmann; C Rhodes; P Berg
Journal:  J Mol Biol       Date:  1977-06-15       Impact factor: 5.469

2.  Transformation of Salmonella typhimurium by plasmid deoxyribonucleic acid.

Authors:  E M Lederberg; S N Cohen
Journal:  J Bacteriol       Date:  1974-09       Impact factor: 3.490

3.  Latent herpes simplex virus in spinal ganglia of mice.

Authors:  J G Stevens; M L Cook
Journal:  Science       Date:  1971-08-27       Impact factor: 47.728

4.  Herpes simplex virus DNA sequences in the CNS of latently infected mice.

Authors:  C V Cabrera; C Wohlenberg; H Openshaw; M Rey-Mendez; A Puga; A L Notkins
Journal:  Nature       Date:  1980-11-20       Impact factor: 49.962

5.  Herpes simplex encephalitis. An immunohistological study of the distribution of viral antigen within the brain.

Authors:  M M Esiri
Journal:  J Neurol Sci       Date:  1982-05       Impact factor: 3.181

6.  "Limbic predilection in Alzheimer dementia: is reactivated herpesvirus involved?".

Authors:  M J Ball
Journal:  Can J Neurol Sci       Date:  1982-08       Impact factor: 2.104

7.  Detection of herpes-simplex viral genome in brain tissue.

Authors:  L W Sequiera; L C Jennings; L H Carrasco; M A Lord; A Curry; R N Sutton
Journal:  Lancet       Date:  1979-09-22       Impact factor: 79.321

8.  Nucleic acid homology studies of viral nucleic acids in idiopathic Parkinson's disease.

Authors:  J G Wetmur; J Schwartz; T S Elizan
Journal:  Arch Neurol       Date:  1979-08

9.  Search for cytomegalovirus and herpes simplex virus genetic information in multiple sclerosis.

Authors:  G S Aulakh; P Albrecht; W W Tourtellotte
Journal:  Neurology       Date:  1980-05       Impact factor: 9.910

10.  Herpes simplex type 1 DNA in human brain tissue.

Authors:  N W Fraser; W C Lawrence; Z Wroblewska; D H Gilden; H Koprowski
Journal:  Proc Natl Acad Sci U S A       Date:  1981-10       Impact factor: 11.205
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  10 in total

1.  The widening spectrum of infectious neurological disease.

Authors:  P G Kennedy
Journal:  J Neurol Neurosurg Psychiatry       Date:  1990-08       Impact factor: 10.154

2.  Recovery and measurement of RNA in Alzheimer's disease by molecular hybridisation.

Authors:  G R Taylor; G I Carter; T J Crow; J A Johnson; A F Fairbairn; E K Perry; R H Perry
Journal:  J Neurol Neurosurg Psychiatry       Date:  1987-03       Impact factor: 10.154

Review 3.  Herpes simplex virus infections and Alzheimer's disease. Implications for drug treatment and immunotherapy.

Authors:  M A Leissring; M C Sugarman; F M LaFerla
Journal:  Drugs Aging       Date:  1998-09       Impact factor: 3.923

4.  Search for viral nucleic acid sequences in the post mortem brains of patients with schizophrenia and individuals who have committed suicide.

Authors:  G I Carter; G R Taylor; T J Crow
Journal:  J Neurol Neurosurg Psychiatry       Date:  1987-03       Impact factor: 10.154

5.  Herpes simplex virus: a role in the aetiology of Alzheimer's disease?

Authors:  G W Roberts; G R Taylor; G I Carter; J A Johnson; C Bloxham; R Brown; T J Crow
Journal:  J Neurol Neurosurg Psychiatry       Date:  1986-02       Impact factor: 10.154

Review 6.  On the issue of transmissibility of Alzheimer disease: a critical review.

Authors:  Christian Schmidt; André Karch; Carsten Korth; Inga Zerr
Journal:  Prion       Date:  2012-10-10       Impact factor: 3.931

Review 7.  Pathogenesis of Alzheimer's disease--beyond the cholinergic hypothesis: discussion paper.

Authors:  P J Harrison
Journal:  J R Soc Med       Date:  1986-06       Impact factor: 5.344

Review 8.  Can infections cause Alzheimer's disease?

Authors:  Francis Mawanda; Robert Wallace
Journal:  Epidemiol Rev       Date:  2013-01-24       Impact factor: 6.222

Review 9.  Possible factors in the etiology of Alzheimer's disease.

Authors:  R F Itzhaki
Journal:  Mol Neurobiol       Date:  1994 Aug-Dec       Impact factor: 5.590

10.  Application of a bioinformatic pipeline to RNA-seq data identifies novel virus-like sequence in human blood.

Authors:  Marko Melnick; Patrick Gonzales; Thomas J LaRocca; Yuping Song; Joanne Wuu; Michael Benatar; Björn Oskarsson; Leonard Petrucelli; Robin D Dowell; Christopher D Link; Mercedes Prudencio
Journal:  G3 (Bethesda)       Date:  2021-09-06       Impact factor: 3.154
  10 in total

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