Literature DB >> 6094686

Isolation and bacterial expression of a murine alpha leukocyte interferon gene.

B Daugherty, D Martin-Zanca, B Kelder, K Collier, T C Seamans, K Hotta, S Pestka.   

Abstract

A murine alpha interferon gene (MuIFN-alpha A) was isolated from a murine genomic DNA library in phage lambda. The gene was cloned and its sequence determined. It was expressed in Escherichia coli under the control of the trp promoter/operator which resulted in antiviral activity on mouse L-cells. MuIFN-alpha A exhibits 60% homology to HuIFN-alpha A at the amino acid level.

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Year:  1984        PMID: 6094686     DOI: 10.1089/jir.1984.4.635

Source DB:  PubMed          Journal:  J Interferon Res        ISSN: 0197-8357


  5 in total

1.  Interferon structural genes do not participate in quantitative regulation of interferon production by If loci as shown in C57BL/6 mice that are congenic with BALB/c mice at the alpha interferon gene cluster.

Authors:  J De Maeyer-Guignard; F Dandoy; D W Bailey; E De Maeyer
Journal:  J Virol       Date:  1986-06       Impact factor: 5.103

2.  Organization, structure and expression of murine interferon alpha genes.

Authors:  E C Zwarthoff; A T Mooren; J Trapman
Journal:  Nucleic Acids Res       Date:  1985-02-11       Impact factor: 16.971

3.  Characterization of the murine alpha interferon gene family.

Authors:  Vincent van Pesch; Hanane Lanaya; Jean-Christophe Renauld; Thomas Michiels
Journal:  J Virol       Date:  2004-08       Impact factor: 5.103

4.  Segregation of restriction fragment length polymorphism in an interspecies cross of laboratory and wild mice indicates tight linkage of the murine IFN-beta gene to the murine IFN-alpha genes.

Authors:  F Dandoy; E De Maeyer; F Bonhomme; J L Guenet; J De Maeyer-Guignard
Journal:  J Virol       Date:  1985-10       Impact factor: 5.103

5.  Molecular and functional analysis of an interferon gene from the zebrafish, Danio rerio.

Authors:  Stephen M Altmann; Mark T Mellon; Daniel L Distel; Carol H Kim
Journal:  J Virol       Date:  2003-02       Impact factor: 5.103

  5 in total

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