Literature DB >> 6094231

The ouabain-sensitive component of synaptosomal respiration.

M Kálmán.   

Abstract

The relationship of oxygen consumption with the activity of the synaptic Na-K-pump was investigated in rat cortical synaptosomes. Changes in oxygen consumption were monitored during the restitution of physiological ionic equilibrium in incubated synaptosomes and under the effects of ouabain and protoveratrine. The ouabain-sensitive component of synaptosomal respiration was measured and correlated with earlier data on synaptosomal K+-uptake. This ouabain-sensitive component was shown to reflect the activity of the Na-K-pump. Our results thus provide a means for the continuous monitoring of ion-pump activity in intact synaptosomes.

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Year:  1984        PMID： 6094231     DOI： 10.1007/bf00237995

Source DB:  PubMed          Journal:  Exp Brain Res        ISSN： 0014-4819            Impact factor:   1.972


  17 in total

1.  Biochemical and morphological studies of the short and long term survival of isolated nerve-endings.

Authors:  H F Bradford; D G Jones; H K Ward; J Booher
Journal:  Brain Res       Date:  1975-06-13       Impact factor: 3.252

2.  An improved method for the preparation of synaptosomal fractions in high purity.

Authors:  F Hajós
Journal:  Brain Res       Date:  1975-08-15       Impact factor: 3.252

3.  Stimulated incorporation of amino acids into proteins of synaptosomal fractions induced by depolarizing treatments.

Authors:  E Wedege; Y Luqmani; H F Bradford
Journal:  J Neurochem       Date:  1977-09       Impact factor: 5.372

4.  Depolarizing stimuli and the release of physiologically active amino acids from suspensions of mammalian synaptosomes.

Authors:  H F Bradford; G W Bennett; A J Thomas
Journal:  J Neurochem       Date:  1973-09       Impact factor: 5.372

5.  Development of Na+-stimulated glucose oxidation in synaptosomes.

Authors:  I Diamond; R A Fishman
Journal:  J Neurochem       Date:  1973-11       Impact factor: 5.372

6.  Metabolic response of synaptosomes to electrical stimulation: release of amino acids.

Authors:  H F Bradford
Journal:  Brain Res       Date:  1970-04-14       Impact factor: 3.252

7.  Glutamine--a major substrate for nerve endings.

Authors:  H F Bradford; H K Ward; A J Thomas
Journal:  J Neurochem       Date:  1978-06       Impact factor: 5.372

8.  Comparative studies of fresh and postmortem isolated rat cortical synaptosomes: morphology, K+ transport, and respiration.

Authors:  M Kálmán; F Hajós
Journal:  J Neurochem       Date:  1982-12       Impact factor: 5.372

9.  Membrane potentials in pinched-off presynaptic nerve ternimals monitored with a fluorescent probe: evidence that synaptosomes have potassium diffusion potentials.

Authors:  M P Blaustein; J M Goldring
Journal:  J Physiol       Date:  1975-06       Impact factor: 5.182

10.  The effect of gamma-aminobutyric acid on the potassium movements of rat cortical synaptosomes.

Authors:  P V Tozalakian; A Csillag
Journal:  Exp Brain Res       Date:  1982       Impact factor: 1.972
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  3 in total

1.  Effect of calcium on Na-K-ATPase activity in depolarized rat cortical synaptosomes as determined on the basis of oxygen consumption.

Authors:  M Kálmán
Journal:  Exp Brain Res       Date:  1985       Impact factor: 1.972

2.  Mitochondria are more resistant to hypoxic depolarization in the newborn than in the adult brain.

Authors:  Geir Arne Larsen; Håvard K Skjellegrind; Morten Larsen Vinje; Jon Berg-Johnsen
Journal:  Neurochem Res       Date:  2008-03-25       Impact factor: 3.996

3.  A fraction enriched in dendrodendritic synaptosomes isolated from rat olfactory bulb: morphology and transmitter release.

Authors:  M D Chiflikian; M Kálmán; A A Galoyan; F Hajós
Journal:  Neurochem Res       Date:  1986-11       Impact factor: 3.996
  3 in total

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